Cellular and Molecular Imaging with SPECT and PET in Brain Tumors

Mohammad S. Sadaghiani; Sara Sheikhbahaei; Steven Rowe; Martin Pomper; Lilja B. Solnes

doi:10.1016/j.rcl.2021.01.005

Cellular and Molecular Imaging with SPECT and PET in Brain Tumors

Mohammad S. Sadaghiani, Sara Sheikhbahaei, Steven Rowe, Martin Pomper, Lilja B. Solnes

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

This review highlights the 2 major molecular imaging modalities that are used in clinics, namely single-photon emission computed tomography (SPECT) and positron emission tomography (PET), and their added value in management of patients with brain tumors. There are a variety of SPECT and PET radiotracers that can allow imaging of different molecular processes. Those radiotracers target specific molecular features of tumors, resulting in improved specificity of these agents. Potential applications include staging of brain tumors and evaluating post-therapeutic changes.

Original language	English (US)
Pages (from-to)	363-375
Number of pages	13
Journal	Radiologic clinics of North America
Volume	59
Issue number	3
DOIs	https://doi.org/10.1016/j.rcl.2021.01.005
State	Published - May 2021

Keywords

Brain tumor
Molecular imaging
PET
SPECT

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.rcl.2021.01.005

Cite this

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title = "Cellular and Molecular Imaging with SPECT and PET in Brain Tumors",

abstract = "This review highlights the 2 major molecular imaging modalities that are used in clinics, namely single-photon emission computed tomography (SPECT) and positron emission tomography (PET), and their added value in management of patients with brain tumors. There are a variety of SPECT and PET radiotracers that can allow imaging of different molecular processes. Those radiotracers target specific molecular features of tumors, resulting in improved specificity of these agents. Potential applications include staging of brain tumors and evaluating post-therapeutic changes.",

keywords = "Brain tumor, Molecular imaging, PET, SPECT",

author = "Sadaghiani, {Mohammad S.} and Sara Sheikhbahaei and Steven Rowe and Martin Pomper and Solnes, {Lilja B.}",

note = "Funding Information: L.B. Solnes is a consultant for Progenics and AAA/Novartis Pharmaceuticals.",

year = "2021",

month = may,

doi = "10.1016/j.rcl.2021.01.005",

language = "English (US)",

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journal = "Radiologic clinics of North America",

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T1 - Cellular and Molecular Imaging with SPECT and PET in Brain Tumors

AU - Sadaghiani, Mohammad S.

AU - Sheikhbahaei, Sara

AU - Rowe, Steven

AU - Pomper, Martin

AU - Solnes, Lilja B.

N1 - Funding Information: L.B. Solnes is a consultant for Progenics and AAA/Novartis Pharmaceuticals.

PY - 2021/5

Y1 - 2021/5

N2 - This review highlights the 2 major molecular imaging modalities that are used in clinics, namely single-photon emission computed tomography (SPECT) and positron emission tomography (PET), and their added value in management of patients with brain tumors. There are a variety of SPECT and PET radiotracers that can allow imaging of different molecular processes. Those radiotracers target specific molecular features of tumors, resulting in improved specificity of these agents. Potential applications include staging of brain tumors and evaluating post-therapeutic changes.

AB - This review highlights the 2 major molecular imaging modalities that are used in clinics, namely single-photon emission computed tomography (SPECT) and positron emission tomography (PET), and their added value in management of patients with brain tumors. There are a variety of SPECT and PET radiotracers that can allow imaging of different molecular processes. Those radiotracers target specific molecular features of tumors, resulting in improved specificity of these agents. Potential applications include staging of brain tumors and evaluating post-therapeutic changes.

KW - Brain tumor

KW - Molecular imaging

KW - PET

KW - SPECT

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DO - 10.1016/j.rcl.2021.01.005

M3 - Review article

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AN - SCOPUS:85105103764

SN - 0033-8389

VL - 59

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EP - 375

JO - Radiologic clinics of North America

JF - Radiologic clinics of North America

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ER -

Cellular and Molecular Imaging with SPECT and PET in Brain Tumors

Abstract

Keywords

ASJC Scopus subject areas

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