Cellular and molecular imaging using chemical exchange saturation transfer

Michael T. McMahon, Assaf A. Gilad

Research output: Contribution to journalReview articlepeer-review


Chemical exchange saturation transfer (CEST) is a powerful new tool well suited for molecular imaging. This technology enables the detection of low concentration probes through selective labeling of rapidly exchanging protons or other spins on the probes. In this review, we will highlight the unique features of CEST imaging technology and describe the different types of CESTagents that are suited for molecular imaging studies, including CEST theranostic agents, CEST reporter genes, and CEST environmental sensors. Key Words: chemical exchange saturation transfer, contrast agents, diaCEST, molecular imaging, paraCEST (Top Magn Reson Imaging 2016;25:197-204)

Original languageEnglish (US)
Pages (from-to)197-204
Number of pages8
JournalTopics in Magnetic Resonance Imaging
Issue number5
StatePublished - Nov 1 2016

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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