Cell-mediated cytotoxic responses of spleen cells from mice bearing primary, chemically induced tumors

C. I. Civin; N. Dorfman; A. Eggers; K. Fink; D. Penvose; C. K. Hsu; J. R. Wunderlich

Cell-mediated cytotoxic responses of spleen cells from mice bearing primary, chemically induced tumors

C. I. Civin, N. Dorfman, A. Eggers, K. Fink, D. Penvose, C. K. Hsu, J. R. Wunderlich

Research output: Contribution to journal › Article › peer-review

Abstract

Sarcomas were induced in C57BL/6 mice by using 3-methylcholanthrene. Spleen cells taken from these mice bearing primary, chemically induced tumors and from matched control mice were assessed for the capacity to generate cell-mediated cytotoxic cell activity after in vitro sensitization. Spleen cells from tumor-bearing mice generated strong cell-mediated cytotoxic responses against alloantigens and antigens on syngeneic cells.

Original language	English (US)
Pages (from-to)	2550-2557
Number of pages	8
Journal	Journal of Immunology
Volume	123
Issue number	6
State	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology

Cite this

@article{088bc56e26534673851f7303a9e1b514,

title = "Cell-mediated cytotoxic responses of spleen cells from mice bearing primary, chemically induced tumors",

abstract = "Sarcomas were induced in C57BL/6 mice by using 3-methylcholanthrene. Spleen cells taken from these mice bearing primary, chemically induced tumors and from matched control mice were assessed for the capacity to generate cell-mediated cytotoxic cell activity after in vitro sensitization. Spleen cells from tumor-bearing mice generated strong cell-mediated cytotoxic responses against alloantigens and antigens on syngeneic cells.",

author = "Civin, {C. I.} and N. Dorfman and A. Eggers and K. Fink and D. Penvose and Hsu, {C. K.} and Wunderlich, {J. R.}",

year = "1979",

language = "English (US)",

volume = "123",

pages = "2550--2557",

journal = "Journal of Immunology",

issn = "0022-1767",

publisher = "American Association of Immunologists",

number = "6",

}

TY - JOUR

T1 - Cell-mediated cytotoxic responses of spleen cells from mice bearing primary, chemically induced tumors

AU - Civin, C. I.

AU - Dorfman, N.

AU - Eggers, A.

AU - Fink, K.

AU - Penvose, D.

AU - Hsu, C. K.

AU - Wunderlich, J. R.

PY - 1979

Y1 - 1979

N2 - Sarcomas were induced in C57BL/6 mice by using 3-methylcholanthrene. Spleen cells taken from these mice bearing primary, chemically induced tumors and from matched control mice were assessed for the capacity to generate cell-mediated cytotoxic cell activity after in vitro sensitization. Spleen cells from tumor-bearing mice generated strong cell-mediated cytotoxic responses against alloantigens and antigens on syngeneic cells.

AB - Sarcomas were induced in C57BL/6 mice by using 3-methylcholanthrene. Spleen cells taken from these mice bearing primary, chemically induced tumors and from matched control mice were assessed for the capacity to generate cell-mediated cytotoxic cell activity after in vitro sensitization. Spleen cells from tumor-bearing mice generated strong cell-mediated cytotoxic responses against alloantigens and antigens on syngeneic cells.

UR - http://www.scopus.com/inward/record.url?scp=0018609988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018609988&partnerID=8YFLogxK

M3 - Article

C2 - 159318

AN - SCOPUS:0018609988

VL - 123

SP - 2550

EP - 2557

JO - Journal of Immunology

JF - Journal of Immunology

SN - 0022-1767

IS - 6

ER -

Cell-mediated cytotoxic responses of spleen cells from mice bearing primary, chemically induced tumors

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this