@inproceedings{fe0c257a050b4fe0a149623b61c3c47a,
title = "Cell death induced by prosthetic metal ions in human chondrocytes",
abstract = "The effect of metal ions on chondrocytes obtained from articular and nasal cartilage was evaluated. Cell death was evaluated by the lactate dyhydrogenase assay (LDH). Cells were incubated with metal ions such as cobalt (Co[II]), chromium (Cr[III]) and chromium (Cr[VI]). It was found that Co[II] and Cr[VI] ions induce chondrocyte death and that the nitric oxide pathway may be involved in the induction of lethal damage. The results show that exposure to critical concentrations of certain types of metal ions results in chondrocyte death, which could lead to the degradation of healthy cartilage.",
author = "P. Lonu and A. Srinivas and M. Overstreet and M. Hungerford and Frondoza, {C. G.}",
year = "2004",
month = dec,
day = "1",
language = "English (US)",
isbn = "1877040193",
series = "Transactions - 7th World Biomaterials Congress",
booktitle = "Transactions - 7th World Biomaterials Congress",
note = "Transactions - 7th World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",
}