@inbook{476885c7d7c440e9855ba531e8685ea7,
title = "Cell-based measurements of mitochondrial function in human subjects",
abstract = "There is growing evidence in the basic science field that aberrant metabolism plays an important role in tumorigenesis. Therefore, it is imperative to perform investigations in human subjects to determine (1) whether the metabolic observations made in model systems are applicable to humans; and (2) if indeed applicable, whether the metabolic alterations are clinically significant for cancer development. As an initial step, here we describe methods for measuring the mitochondrial metabolism of blood lymphocytes and skeletal muscle myoblasts that can be obtained from human subjects.",
keywords = "Human, Lymphocytes, Mitochondria, Myoblasts, Respiration",
author = "Kang, {Ju Gyeong} and Wang, {Ping Yuan} and Hwang, {Paul M.}",
note = "Funding Information: This work was supported by the Division of Intramural Research, National Heart, Lung, and Blood Institutes (NHLBI), National Institutes of Health. We thank Martin Pelletier and Kim K. Han for helpful advice with the Seahorse XF Analyzer protocol.",
year = "2014",
doi = "10.1016/B978-0-12-416618-9.00011-X",
language = "English (US)",
isbn = "9780124166189",
series = "Methods in Enzymology",
publisher = "Academic Press Inc.",
pages = "209--221",
booktitle = "Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism",
}