CD79a+ T-cell lymphoblastic lymphoma with coexisting Langerhans cell histiocytosis: A short case report and review of the literature

Research output: Contribution to journalArticlepeer-review

Abstract

Although there is a close association between Langerhans cell histiocytosis and malignant neoplasms, simultaneous occurrence of lymphoblastic lymphoma and Langerhans cell histiocytosis in the same lymph node is an extremely rare finding. Herein, we describe such a case in a 26-year-old woman who presented with progressive cervical lymphadenopathy. The lymphoma cells have an immature T-cell phenotype (terminal deoxynucleotidyl transferase+, HLA-DR+, CD34+, CD38+, and CD7+) with expression of both CD3 and CD79a on immunohistochemical stain. The Langerhans cells are present focally with the characteristic morphologic features and immunophenotype (CD1a+ and S100+). The significance of CD79a coexpression in T-cell lymphoblastic lymphoma and the association between lymphoblastic lymphoma and Langerhans cell histiocytosis are discussed.

Original languageEnglish (US)
Pages (from-to)958-960
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume125
Issue number7
StatePublished - Jul 19 2001
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Fingerprint Dive into the research topics of 'CD79a<sup>+</sup> T-cell lymphoblastic lymphoma with coexisting Langerhans cell histiocytosis: A short case report and review of the literature'. Together they form a unique fingerprint.

Cite this