CD4+ T cell depletion in an untreated HIV type 1-infected human leukocyte antigen-B*5801-positive patient with an undetectable viral load

Adriana Andrade, Justin R. Bailey, Jie Xu, Frances H. Philp, Thomas C. Quinn, Thomas M. Williams, Stuart C. Ray, David L. Thomas, Joel N. Blankson

Research output: Contribution to journalArticle


We report a case of a patient infected with human immunodeficiency virus type 1 (HIV-1) for 20 years who has experienced CD4+ T cell depletion in spite of maintaining undetectable viral loads. Our data suggest that immune activation can cause CD4+ T cell depletion even when HIV-1 replication appears to be controlled by host factors.

Original languageEnglish (US)
Pages (from-to)e78-e82
JournalClinical Infectious Diseases
Issue number8
StatePublished - Apr 15 2008


ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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