CD4+ T cell depletion in an untreated HIV type 1-infected human leukocyte antigen-B*5801-positive patient with an undetectable viral load

Adriana Andrade, Justin R. Bailey, Jie Xu, Frances H. Philp, Thomas C. Quinn, Thomas M. Williams, Stuart C. Ray, David L. Thomas, Joel N. Blankson

Research output: Contribution to journalArticle

Abstract

We report a case of a patient infected with human immunodeficiency virus type 1 (HIV-1) for 20 years who has experienced CD4+ T cell depletion in spite of maintaining undetectable viral loads. Our data suggest that immune activation can cause CD4+ T cell depletion even when HIV-1 replication appears to be controlled by host factors.

Original languageEnglish (US)
Pages (from-to)e78-e82
JournalClinical Infectious Diseases
Volume46
Issue number8
DOIs
StatePublished - Apr 15 2008

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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