Abstract
Background: The impact of immune status and surgical outcome in patients with HIV and acquired immunodeficiency syndrome (AIDS) remains unknown. Methods Clinical variables of HIV/AIDS patients undergoing abdominal surgery were examined for their impact on outcome. Results Major abdominal procedures were performed in 77 patients with a diagnosis of HIV/AIDS (55 males, mean age 41.1 years, mean CD4 count 210 mg/dL). A majority of operations (53%) were performed on an urgent basis. Patients undergoing urgent procedures had lower CD4 counts (129 ± 121 vs 303 ± 324, P = .002). The mean CD4 count was lower for patients with complications (146 ± 156 vs 288 ± 319, P = .013) and for those who died (112 ± 113 vs 251 ± 283, P = .026). On multivariate analysis, CD4 count was independently associated with an increased risk for complication, and urgent operation was associated with an increased risk for mortality. Conclusion Patients with HIV/AIDS who had lower CD4 counts were more likely to require an urgent operation and experience a complication with increased mortality.
Original language | English (US) |
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Pages (from-to) | 694-700 |
Number of pages | 7 |
Journal | American journal of surgery |
Volume | 200 |
Issue number | 6 |
DOIs | |
State | Published - Dec 2010 |
Externally published | Yes |
Keywords
- Abdominal surgery
- Acquired immunodeficiency syndrome
- CD4
- HIV
- Immune status
ASJC Scopus subject areas
- Surgery