@article{c11f78125c1242bead43d14d6737cca2,
title = "CCR2 genotype and disease progression in a treated population of HIV type 1-infected women",
abstract = "Both antiretroviral therapy and the human coreceptor polymorphism CCR2-V64I slow progression of human immunodeficiency virus type 1 (HIV-1) disease. To examine the effect of V64I on disease progression in patients receiving therapy, we determined CCR2 genotypes in the Women's Interagency HIV Study cohort. We studied 2047 HIV-1-infected women, most of whom initiated treatment during the study. No association was seen between CCR2 genotype and either disease progression or therapeutic response, suggesting that the benefits of treatment most likely overshadow the salutary effects of the V64I polymorphism.",
author = "Sean Philpott and Harold Burger and Tarwater, {Patrick M.} and Ming Lu and Gange, {Stephen J.} and Kathryn Anastos and Mardge Cohen and Greenblatt, {Ruth M.} and Andrea Kovacs and Howard Minkoff and Mary Young and Paolo Miotti and Michelle Dupuis and Barbara Weiser",
note = "Funding Information: Financial support. National Institute of Allergy and Infectious Diseases, with supplemental funding from the National Cancer Institute, the National Institute of Child Health & Human Development, the National Institute on Drug Abuse, the National Institute of Craniofacial and Dental Research (grants U01-AI-35004, U01-AI-31834, U01-AI-34994, U01-AI-34989, U01-HD-32632, U01-AI-34993, U01-AI-42590, M01-RR00079, and M01-RR00083; and grant RO1-AI-42555 [to H.B.]), and a National Research Service Award (grant 1 F32 HD08478-01; to S.P.). Conflict of interest. All authors: No conflict.",
year = "2004",
month = sep,
day = "15",
doi = "10.1086/423386",
language = "English (US)",
volume = "39",
pages = "861--865",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "6",
}