CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer

Clint T. Allen, Barbara Conley, John B. Sunwoo, Carter Van Waes

Research output: Contribution to journalReview article

Abstract

In a study published in the May 1, 2001, issue of Clinical Cancer Research, Sunwoo and colleagues provided evidence for proteasome inhibition of NF-kB and tumorigenesis, supporting early-phase clinical trials in solid malignancies of the upper aerodigestive tract. Subsequent clinical studies uncovered a dichotomy of responses in patients with hematopoietic and solid malignancies, and the mechanisms of resistance.

Original languageEnglish (US)
Pages (from-to)942-943
Number of pages2
JournalClinical Cancer Research
Volume21
Issue number5
DOIs
StatePublished - Mar 1 2015

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'CCR 20<sup>th</sup> anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer'. Together they form a unique fingerprint.

  • Cite this