Causal interactions between thalamic and cortical LFPs following hypoxic-ischemic brain injury

Dan Wu, anastasios Bezerianos, David Sherman, Xiaofeng Jia, Nitish V. Thakor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Asphyxial cardiac arrest (CA) introduces a global hypoxic-ischemic insult to the brain and disturbs the neural networks. We analyzed the thalamocortical interactions in a rat model of asphyxial CA, using the local field potentials recorded from the thalamus and cortex during CA and the recovery periods. The direct Directed Transfer Function (dDTF) and Directed Information Flow (DIF) were applied to characterize the causal coherence and causal mutual information of the network, respectively. Key results from dDTF and DIF analyses suggest from complementary perspectives that the thalamus may play a leading role in arousal in an ischemic brain.

Original languageEnglish (US)
Title of host publication2011 5th International IEEE/EMBS Conference on Neural Engineering, NER 2011
Pages184-187
Number of pages4
DOIs
StatePublished - Jul 20 2011
Event2011 5th International IEEE/EMBS Conference on Neural Engineering, NER 2011 - Cancun, Mexico
Duration: Apr 27 2011May 1 2011

Publication series

Name2011 5th International IEEE/EMBS Conference on Neural Engineering, NER 2011

Other

Other2011 5th International IEEE/EMBS Conference on Neural Engineering, NER 2011
Country/TerritoryMexico
CityCancun
Period4/27/115/1/11

ASJC Scopus subject areas

  • Neuroscience(all)

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