Abstract
In this issue of Structure, Petrella et al. (2019) determine the structure of a catalytically competent construct of M. tuberculosis gyrase. Surprisingly, both apo and AMPPNP-bound structures capture a previously unknown enzyme state that is stabilized by a domain insertion unique to Corynebacteriales and appears to help regulate ATPase cycling.
Original language | English (US) |
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Pages (from-to) | 561-563 |
Number of pages | 3 |
Journal | Structure |
Volume | 27 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2 2019 |
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology