Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

Jawad U. Khan; Clifford M. Takemoto; James F. Casella; Michael B. Streiff; Ikechi J. Nwankwo; Hyun S. Kim

doi:10.1007/s00270-007-9229-9

Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

Jawad U. Khan, Clifford M. Takemoto, James F. Casella, Michael B. Streiff, Ikechi J. Nwankwo, Hyun S. Kim

School of Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.

Original language	English (US)
Pages (from-to)	S153-S160
Journal	Cardiovascular and interventional radiology
Volume	31
Issue number	SUPPL.2
DOIs	https://doi.org/10.1007/s00270-007-9229-9
State	Published - Jul 2008

Keywords

Catheter-directed thrombolysis
Inferior vena cava thrombosis
Neonate

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

Access to Document

10.1007/s00270-007-9229-9

Cite this

@article{19e833b040084ffb95b300c2f23e818c,

title = "Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature",

abstract = "Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.",

keywords = "Catheter-directed thrombolysis, Inferior vena cava thrombosis, Neonate",

author = "Khan, {Jawad U.} and Takemoto, {Clifford M.} and Casella, {James F.} and Streiff, {Michael B.} and Nwankwo, {Ikechi J.} and Kim, {Hyun S.}",

year = "2008",

month = jul,

doi = "10.1007/s00270-007-9229-9",

language = "English (US)",

volume = "31",

pages = "S153--S160",

journal = "Cardiovascular and interventional radiology",

issn = "0174-1551",

publisher = "Springer Verlag",

number = "SUPPL.2",

}

TY - JOUR

T1 - Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

AU - Khan, Jawad U.

AU - Takemoto, Clifford M.

AU - Casella, James F.

AU - Streiff, Michael B.

AU - Nwankwo, Ikechi J.

AU - Kim, Hyun S.

PY - 2008/7

Y1 - 2008/7

N2 - Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.

AB - Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.

KW - Catheter-directed thrombolysis

KW - Inferior vena cava thrombosis

KW - Neonate

UR - http://www.scopus.com/inward/record.url?scp=48449093346&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48449093346&partnerID=8YFLogxK

U2 - 10.1007/s00270-007-9229-9

DO - 10.1007/s00270-007-9229-9

M3 - Article

C2 - 18004620

AN - SCOPUS:48449093346

SN - 0174-1551

VL - 31

SP - S153-S160

JO - Cardiovascular and interventional radiology

JF - Cardiovascular and interventional radiology

IS - SUPPL.2

ER -

Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this