Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

Jawad U. Khan, Clifford M Takemoto, James F Casella, Michael B Streiff, Ikechi J. Nwankwo, Hyun S. Kim

Research output: Contribution to journalArticle

Abstract

Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.

Original languageEnglish (US)
JournalCardioVascular and Interventional Radiology
Volume31
Issue numberSUPPL.2
DOIs
StatePublished - Jul 2008

Fingerprint

Inferior Vena Cava
Thrombosis
Catheters
Newborn Infant
Tissue Plasminogen Activator
Antithrombin III Deficiency
Critical Illness
Venous Thrombosis
Oxidoreductases
Morbidity
Mutation
Genes

Keywords

  • Catheter-directed thrombolysis
  • Inferior vena cava thrombosis
  • Neonate

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature. / Khan, Jawad U.; Takemoto, Clifford M; Casella, James F; Streiff, Michael B; Nwankwo, Ikechi J.; Kim, Hyun S.

In: CardioVascular and Interventional Radiology, Vol. 31, No. SUPPL.2, 07.2008.

Research output: Contribution to journalArticle

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