Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

Jawad U. Khan; Clifford M. Takemoto; James F. Casella; Michael B. Streiff; Ikechi J. Nwankwo; Hyun S. Kim

doi:10.1007/s00270-007-9229-9

Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

Jawad U. Khan, Clifford M. Takemoto, James F. Casella, Michael B. Streiff, Ikechi J. Nwankwo, Hyun S. Kim

School of Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.

Original language	English (US)
Pages (from-to)	S153-S160
Journal	Cardiovascular and interventional radiology
Volume	31
Issue number	SUPPL.2
DOIs	https://doi.org/10.1007/s00270-007-9229-9
State	Published - Jul 1 2008

Keywords

Catheter-directed thrombolysis
Inferior vena cava thrombosis
Neonate

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1007/s00270-007-9229-9

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abstract = "Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.",

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AU - Khan, Jawad U.

AU - Takemoto, Clifford M.

AU - Casella, James F.

AU - Streiff, Michael B.

AU - Nwankwo, Ikechi J.

AU - Kim, Hyun S.

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AB - Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.

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Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature

Abstract

Keywords

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