Catatonia in an adolescent with velo-cardio-facial syndrome

Gianni L. Faedda, Lee E. Wachtel, Anne Marie Higgins, Robert J. Shprintzen

Research output: Research - peer-reviewArticle

Abstract

Velo-cardio-facial syndrome (VCFS) is the most common microdeletion syndrome in humans and is probably the most frequent genetic cause of psychosis currently known. Many psychiatric disorders have been reported to occur in people with VCFS including, but not limited to schizophrenia, unipolar and bipolar mood disorders (with or without psychotic features), schizoaffective disorder, psychosis NOS, social phobia, generalized and separation anxiety, obsessive-compulsive disorder, autism spectrum disorder, cognitive impairment, and ADHD. This report describes the psychiatric onset and development of catatonia in an adolescent female with VCFS that was undiagnosed until 15 years of age. Catatonia may be a relatively common presentation in people with VCFS with treatment-refractory psychiatric manifestations.

LanguageEnglish (US)
Pages2150-2153
Number of pages4
JournalAmerican Journal of Medical Genetics, Part A
Volume167
Issue number9
DOIs
StatePublished - Sep 1 2015

Fingerprint

Catatonia
DiGeorge Syndrome
Psychotic Disorders
Psychiatry
Separation Anxiety
Obsessive-Compulsive Disorder
Mood Disorders
Bipolar Disorder
Schizophrenia
Therapeutics
Cognitive Dysfunction
Social Phobia
Autism Spectrum Disorder

Keywords

  • 22q11.2 deletion
  • Catatonia
  • Psychosis
  • Velo-cardio-facial syndrome

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Catatonia in an adolescent with velo-cardio-facial syndrome. / Faedda, Gianni L.; Wachtel, Lee E.; Higgins, Anne Marie; Shprintzen, Robert J.

In: American Journal of Medical Genetics, Part A, Vol. 167, No. 9, 01.09.2015, p. 2150-2153.

Research output: Research - peer-reviewArticle

Faedda GL, Wachtel LE, Higgins AM, Shprintzen RJ. Catatonia in an adolescent with velo-cardio-facial syndrome. American Journal of Medical Genetics, Part A. 2015 Sep 1;167(9):2150-2153. Available from, DOI: 10.1002/ajmg.a.37087
Faedda, Gianni L. ; Wachtel, Lee E. ; Higgins, Anne Marie ; Shprintzen, Robert J./ Catatonia in an adolescent with velo-cardio-facial syndrome. In: American Journal of Medical Genetics, Part A. 2015 ; Vol. 167, No. 9. pp. 2150-2153
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