Cases of aphasia or neglect due to Creutzfeldt-Jakob disease

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Abstract

Two patients with CJD whose deficits are attributable to damage to selective cognitive mechanisms are described. One patient presented with 'pure word deafness' with severe anemia and progressed to Global aphasia. EEG and SPECT showed left cortical abnormalities. The other presented with progressive left neglect and digressive speech with meager interpretive content, but never developed aphasia. EEG showed right cortical abnormalities. These cases provide evidence that CJD can begin focally and unilaterally. Several cases of progressive aphasia due to CJD have been described, but this may be the first reported case of progressive right hemisphere dysfunction due to CJD.

Original languageEnglish (US)
Pages (from-to)743-754
Number of pages12
JournalAphasiology
Volume13
Issue number9-11
DOIs
StatePublished - Sep 1 1999

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Language and Linguistics
  • Developmental and Educational Psychology
  • Linguistics and Language
  • Neurology
  • Clinical Neurology
  • LPN and LVN

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