Case–control study of cryptosporidium parvum infection in peruvian children hospitalized for diarrhea: Possible association with malnutrition and nosocomial infection

Silvana Sarabia-Arce, Eduardo Salazar-Lindo, Robert H Gilman, Jorge Naranjo, Elba Miranda

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Abstract

A retrospective, hospital-based case-control study was used to investigate whether there were any clinical characteristics that could distinguish Cryptosporidium parvum-infected children with diarrhea from other non-C. parvum-iniected children with diarrhea. Ten percent (24 of 248) of children admitted to a rehydration ward at Cayetano Heredia University Hospital, Lima, Peru, were infected with C. parvum. The 24 patients infected with C. parvum (cases) were matched to an equal number of noninfected patients (controls). C. parvum-infected patients were more likely to be malnourished than were children without this infection (P <0.05). Also nosocomial infection caused by C. parvum occurred in three severely malnourished patients, two of whom died. No other clinical or laboratory characteristics were found that would distinguish children with diarrhea caused by C. parvum from other children with diarrhea. In children hospitalized for diarrhea C. parvuminfection occurs most frequently in malnourished children.

Original languageEnglish (US)
Pages (from-to)627-631
Number of pages5
JournalPediatric Infectious Disease Journal
Volume9
Issue number9
Publication statusPublished - 1990

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Keywords

  • Cryptosporidium
  • Malnutrition
  • Nosocomial infectionl

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Pediatrics, Perinatology, and Child Health

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