Abstract
Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma that commonly affects extranodal sites. The most commonly affected sites are the bone marrow, gastrointestinal tract, Waldeyer's ring, lung, and pleura. We report the case of an 80-year-old diabetic male, in MCL remission, who presented with a small dome-shaped nodule on his calf and an ipsilateral second digit non-healing ulceration after a traumatic fall. Despite surgical and conservative treatment, the wound worsened, resulting in histopathologic examination, which confirmed the presence of lymphocytes, indicating MCL relapse. This case was followed up for approximately 3 months until the patient died. Our case is an example of pedal manifestations of skin involvement of MCL, which, on consideration of the clinical manifestations also, can be confused with a nonhealing diabetic wound. The clinical significance of our case study is to assist in the diagnosis, management, and prognosis of a patient with MCL.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1104-1108 |
| Number of pages | 5 |
| Journal | Journal of Foot and Ankle Surgery |
| Volume | 56 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 1 2017 |
| Externally published | Yes |
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Keywords
- cancer
- lymphoma in foot
- mantle cell lymphoma
- skin involvement
- tumor
ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine
Cite this
Case Study : Rare Case of Mantle Cell Lymphoma With Extranodal Involvement in the Foot. / Fu, Pauline; Mercado, Danielle; Malezhik, Vera; Mannan, Abul Ala Syed Rifat.
In: Journal of Foot and Ankle Surgery, Vol. 56, No. 5, 01.09.2017, p. 1104-1108.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Case Study
T2 - Rare Case of Mantle Cell Lymphoma With Extranodal Involvement in the Foot
AU - Fu, Pauline
AU - Mercado, Danielle
AU - Malezhik, Vera
AU - Mannan, Abul Ala Syed Rifat
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma that commonly affects extranodal sites. The most commonly affected sites are the bone marrow, gastrointestinal tract, Waldeyer's ring, lung, and pleura. We report the case of an 80-year-old diabetic male, in MCL remission, who presented with a small dome-shaped nodule on his calf and an ipsilateral second digit non-healing ulceration after a traumatic fall. Despite surgical and conservative treatment, the wound worsened, resulting in histopathologic examination, which confirmed the presence of lymphocytes, indicating MCL relapse. This case was followed up for approximately 3 months until the patient died. Our case is an example of pedal manifestations of skin involvement of MCL, which, on consideration of the clinical manifestations also, can be confused with a nonhealing diabetic wound. The clinical significance of our case study is to assist in the diagnosis, management, and prognosis of a patient with MCL.
AB - Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma that commonly affects extranodal sites. The most commonly affected sites are the bone marrow, gastrointestinal tract, Waldeyer's ring, lung, and pleura. We report the case of an 80-year-old diabetic male, in MCL remission, who presented with a small dome-shaped nodule on his calf and an ipsilateral second digit non-healing ulceration after a traumatic fall. Despite surgical and conservative treatment, the wound worsened, resulting in histopathologic examination, which confirmed the presence of lymphocytes, indicating MCL relapse. This case was followed up for approximately 3 months until the patient died. Our case is an example of pedal manifestations of skin involvement of MCL, which, on consideration of the clinical manifestations also, can be confused with a nonhealing diabetic wound. The clinical significance of our case study is to assist in the diagnosis, management, and prognosis of a patient with MCL.
KW - cancer
KW - lymphoma in foot
KW - mantle cell lymphoma
KW - skin involvement
KW - tumor
UR - http://www.scopus.com/inward/record.url?scp=85028309915&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85028309915&partnerID=8YFLogxK
U2 - 10.1053/j.jfas.2017.04.019
DO - 10.1053/j.jfas.2017.04.019
M3 - Article
C2 - 28842094
AN - SCOPUS:85028309915
VL - 56
SP - 1104
EP - 1108
JO - Journal of Foot and Ankle Surgery
JF - Journal of Foot and Ankle Surgery
SN - 1067-2516
IS - 5
ER -