Case Study: Rare Case of Mantle Cell Lymphoma With Extranodal Involvement in the Foot

Pauline Fu, Danielle Mercado, Vera Malezhik, Abul Ala Syed Rifat Mannan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma that commonly affects extranodal sites. The most commonly affected sites are the bone marrow, gastrointestinal tract, Waldeyer's ring, lung, and pleura. We report the case of an 80-year-old diabetic male, in MCL remission, who presented with a small dome-shaped nodule on his calf and an ipsilateral second digit non-healing ulceration after a traumatic fall. Despite surgical and conservative treatment, the wound worsened, resulting in histopathologic examination, which confirmed the presence of lymphocytes, indicating MCL relapse. This case was followed up for approximately 3 months until the patient died. Our case is an example of pedal manifestations of skin involvement of MCL, which, on consideration of the clinical manifestations also, can be confused with a nonhealing diabetic wound. The clinical significance of our case study is to assist in the diagnosis, management, and prognosis of a patient with MCL.

Original languageEnglish (US)
Pages (from-to)1104-1108
Number of pages5
JournalJournal of Foot and Ankle Surgery
Issue number5
StatePublished - Sep 2017


  • cancer
  • lymphoma in foot
  • mantle cell lymphoma
  • skin involvement
  • tumor

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


Dive into the research topics of 'Case Study: Rare Case of Mantle Cell Lymphoma With Extranodal Involvement in the Foot'. Together they form a unique fingerprint.

Cite this