TY - JOUR
T1 - Case report
T2 - Sclerosing orbital inflammation caused by Leishmania braziliensis
AU - Cruz, Antonio Augusto V
AU - Alves-Ferreira, Eliza V C
AU - Milbratz-Moré, Gherusa
AU - Chahud, Fernando
AU - Ruy, Patricia C.
AU - Duarte, Maria Irma Seixas
AU - Cruz, Angela Kaysel
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Orbital biopsy of nonspecific orbital inflammation, commonly referred to as "orbital pseudotumor," typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of Leishmania braziliensis and DNA from the parasite.
AB - Orbital biopsy of nonspecific orbital inflammation, commonly referred to as "orbital pseudotumor," typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of Leishmania braziliensis and DNA from the parasite.
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U2 - 10.4269/ajtmh.16-0389
DO - 10.4269/ajtmh.16-0389
M3 - Article
C2 - 27799649
AN - SCOPUS:85011711096
SN - 0002-9637
VL - 96
SP - 197
EP - 199
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 1
ER -