Case report: Kaposi's sarcoma with bone marrow involvement: Occurrence in a patient with the acquired immunodeficiency syndrome

B. J. Little, J. L. Spivak, T. C. Quinn, R. B. Mann

Research output: Contribution to journalArticlepeer-review

Abstract

A patient with the acquired immune deficiency syndrome (AIDS) and the lymphadenopathic variant of Kaposi's sarcoma developed skin, gastrointestinal and pulmonary lesions. A cellular specimen was obtained on bone marrow aspiration, but the bone marrow biopsy revealed dense reticulin fibrosis with slit-like spaces and endothelial-lined channels consistent with Kapsoi's sarcoma. At postmortem examination, Kaposi's sarcoma was found in the pleura and lungs, throughout the gastrointestinal tract, in the liver and spleen, and in the thoracic and abdominal lymph nodes. Bone marrow architecture appeared grossly normal, but microscopic examination revealed numerous foci of Kaposi's sarcoma. This is the first reported example of bone marrow involvement with Kaposi's sarcoma in AIDS recognized antemortem.

Original languageEnglish (US)
Pages (from-to)44-46
Number of pages3
JournalAmerican Journal of the Medical Sciences
Volume292
Issue number1
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Medicine(all)

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