Cascaded systems analysis of the 3D NEQ for cone-beam CT and tomosynthesis

D. J. Tward, Jeff Siewerdsen, R. A. Fahrig, A. R. Pineda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Crucial to understanding the factors that govern imaging performance is a rigorous analysis of signal and noise transfer characteristics (e.g., MTF, NPS, and NEQ) applied to a task-based performance metric (e.g., detectability index). This paper advances a theoretical framework for calculation of the NPS, NEQ, and DQE of cone-beam CT (CBCT) and tomosynthesis based on cascaded systems analysis. The model considers the 2D projection NPS propagated through a series of reconstruction stages to yield the 3D NPS, revealing a continuum (from 2D projection radiography to limitedangle tomosynthesis and fully 3D CBCT) for which NEQ and detectability index may be investigated as a function of any system parameter. Factors considered in the cascade include: system geometry; angular extent of source-detector orbit; finite number of views; log-scaling; application of ramp, apodization, and interpolation filters; back-projection; and 3D noise aliasing - all of which have a direct impact on the 3D NEQ and DQE. Calculations of the 3D NPS were found to agree with experimental measurements across a broad range of imaging conditions. The model presents a theoretical framework that unifies 3D Fourier-based performance metrology in tomosynthesis and CBCT, providing a guide to optimization that rigorously considers the system configuration, reconstruction parameters, and imaging task.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6913
DOIs
StatePublished - 2008
Externally publishedYes
EventMedical Imaging 2008 - Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 18 2008Feb 21 2008

Other

OtherMedical Imaging 2008 - Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/18/082/21/08

Fingerprint

Cones
Systems analysis
Imaging techniques
Radiography
Interpolation
Orbits
Detectors
Geometry

Keywords

  • 3D imaging, imaging performance
  • Cascaded systems analysis
  • Cone-beam CT
  • Flat-panel detector
  • NEQ
  • Noise-equivalent quanta
  • Noise-power spectrum
  • NPS
  • Tomosynthesis

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Tward, D. J., Siewerdsen, J., Fahrig, R. A., & Pineda, A. R. (2008). Cascaded systems analysis of the 3D NEQ for cone-beam CT and tomosynthesis. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6913). [69131S] https://doi.org/10.1117/12.772999

Cascaded systems analysis of the 3D NEQ for cone-beam CT and tomosynthesis. / Tward, D. J.; Siewerdsen, Jeff; Fahrig, R. A.; Pineda, A. R.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6913 2008. 69131S.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tward, DJ, Siewerdsen, J, Fahrig, RA & Pineda, AR 2008, Cascaded systems analysis of the 3D NEQ for cone-beam CT and tomosynthesis. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6913, 69131S, Medical Imaging 2008 - Physics of Medical Imaging, San Diego, CA, United States, 2/18/08. https://doi.org/10.1117/12.772999
Tward DJ, Siewerdsen J, Fahrig RA, Pineda AR. Cascaded systems analysis of the 3D NEQ for cone-beam CT and tomosynthesis. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6913. 2008. 69131S https://doi.org/10.1117/12.772999
Tward, D. J. ; Siewerdsen, Jeff ; Fahrig, R. A. ; Pineda, A. R. / Cascaded systems analysis of the 3D NEQ for cone-beam CT and tomosynthesis. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6913 2008.
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