Cartilaginous differentiation in peritoneal tissues

A report of two cases and a review of the literature

Oluwole Fadare, Carlo Bifulco, Darryl Carter, Vinita Parkash

Research output: Contribution to journalArticle

Abstract

Two cases of cartilaginous differentiation of the peritoneum not associated with an intraabdominal malignancy are described. This is the first detailed report of cartilaginous metaplasia of the peritoneum. The patients were female, ages 53 (Patient 1) and 77 years (Patient 2). Prior medical histories were significant for a culdotomy (to drain pelvic abscesses associated with pelvic inflammatory disease) in Patient 1 and for an open abdominal surgery in Patient 2. The peritoneal lesions were incidental findings in both cases. In Patient 1, surgery was performed for a septated ovarian cyst; the other patient underwent surgery to relieve obstructive bowel symptoms. In Patient 1, multiple firm, white lesions ranging from 2.0 to 7.0 mm were present on the serosal surfaces and the mesenteries of the small and large bowel. In Patient 2, a single firm, white lesion measuring 2 cm in maximum dimension was removed from the mesentery of the ileum. Microscopically, the lesions consisted of small nodules of mature hyaline cartilage surrounded by nondescript fibrous tissue and covered by mesothelium. There was no foreign body giant cell reaction, inflammation, or other reactive changes in the surrounding adipose tissue. These may represent metaplastic lesions of the secondary mullerian system, or a unique peritoneal response to previous surgical manipulation. Alternatively, these may represent benign neoplastic lesions (chondroma) of the submesothelium.

Original languageEnglish (US)
Pages (from-to)777-780
Number of pages4
JournalModern Pathology
Volume15
Issue number7
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

Mesentery
Peritoneum
Foreign Body Giant Cells
Chondroma
Hyaline Cartilage
Pelvic Inflammatory Disease
Ovarian Cysts
Incidental Findings
Metaplasia
Ileum
Abscess
Adipose Tissue
Epithelium
Inflammation
Neoplasms

Keywords

  • Cartilage
  • Cartilaginous metaplasia
  • Heterotopic cartilage
  • Peritoneum

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Cartilaginous differentiation in peritoneal tissues : A report of two cases and a review of the literature. / Fadare, Oluwole; Bifulco, Carlo; Carter, Darryl; Parkash, Vinita.

In: Modern Pathology, Vol. 15, No. 7, 2002, p. 777-780.

Research output: Contribution to journalArticle

Fadare, Oluwole ; Bifulco, Carlo ; Carter, Darryl ; Parkash, Vinita. / Cartilaginous differentiation in peritoneal tissues : A report of two cases and a review of the literature. In: Modern Pathology. 2002 ; Vol. 15, No. 7. pp. 777-780.
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