Carotid artery atherosclerosis: In vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging - Initial results

Bruce A. Wasserman, William I. Smith, Hugh H. Trout, Richard O. Cannon, Robert S. Balaban, Andrew E. Arai

Research output: Contribution to journalArticlepeer-review

Abstract

In nine subjects with carotid atherosclerosis, double-oblique, contrast material-enhanced, double inversion-recovery, fast spin-echo magnetic resonance (MR) images were acquired through atheroma in the proximal internal carotid artery. Fibrocellular tissue within atheroma selectively enhanced 29% after administration of gadolinium-based contrast agent. Contrast enhancement helped discriminate fibrous cap from lipid core with a contrast-to-noise ratio as good as or better than that with T2-weighted MR images but with approximately twice the signal-to-noise ratio (postcontrast images, 36.6 ± 3.6; T2-weighted images, 17.5 ± 2.1; P < .001).

Original languageEnglish (US)
Pages (from-to)566-573
Number of pages8
JournalRADIOLOGY
Volume223
Issue number2
DOIs
StatePublished - 2002

Keywords

  • Arteriosclerosis
  • Magnetic resonance (MR), high-resolution
  • Magnetic resonance (MR), tissue characterization
  • Magnetic resonance (MR), vascular studies

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Carotid artery atherosclerosis: In vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging - Initial results'. Together they form a unique fingerprint.

Cite this