Cardiovascular reactivity to the cold pressor test as a predictor of hypertension

M. S. Menkes, K. A. Matthews, D. S. Krantz, U. Lundberg, A. Mead l., B. Qaqish, K. Y. Liang, C. B. Thomas, T. A. Pearson

Research output: Contribution to journalArticle

Abstract

Cardiovascular reactivity to stress is hypothesized to be a marker for subsequent neurogenic cardiovascular disease, but few prospective studies of this hypothesis are available. We studied 910 white male medical students who had their blood pressure and pulse rate measured before and during a cold pressor test in the years 1948-1964. Hypertensive status (requiring drug treatment) was ascertained by annual questionnaires in to 20- to 36-year follow-up period. An association was observed between maximum change in systolic blood pressure and later hypertension, with a cumulative incidence of hypertension by age 44 of 6.7%, 3.0%, and 2.4% for a change in systolic blood pressure in the upper, middle two, and lowest quartiles, respectively (Kaplan-Meier, p

Original languageEnglish (US)
Pages (from-to)524-530
Number of pages7
JournalHypertension
Volume14
Issue number5
StatePublished - 1989
Externally publishedYes

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Blood Pressure
Hypertension
Medical Students
Cardiovascular Diseases
Heart Rate
Prospective Studies
Incidence
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Menkes, M. S., Matthews, K. A., Krantz, D. S., Lundberg, U., Mead l., A., Qaqish, B., ... Pearson, T. A. (1989). Cardiovascular reactivity to the cold pressor test as a predictor of hypertension. Hypertension, 14(5), 524-530.

Cardiovascular reactivity to the cold pressor test as a predictor of hypertension. / Menkes, M. S.; Matthews, K. A.; Krantz, D. S.; Lundberg, U.; Mead l., A.; Qaqish, B.; Liang, K. Y.; Thomas, C. B.; Pearson, T. A.

In: Hypertension, Vol. 14, No. 5, 1989, p. 524-530.

Research output: Contribution to journalArticle

Menkes, MS, Matthews, KA, Krantz, DS, Lundberg, U, Mead l., A, Qaqish, B, Liang, KY, Thomas, CB & Pearson, TA 1989, 'Cardiovascular reactivity to the cold pressor test as a predictor of hypertension', Hypertension, vol. 14, no. 5, pp. 524-530.
Menkes MS, Matthews KA, Krantz DS, Lundberg U, Mead l. A, Qaqish B et al. Cardiovascular reactivity to the cold pressor test as a predictor of hypertension. Hypertension. 1989;14(5):524-530.
Menkes, M. S. ; Matthews, K. A. ; Krantz, D. S. ; Lundberg, U. ; Mead l., A. ; Qaqish, B. ; Liang, K. Y. ; Thomas, C. B. ; Pearson, T. A. / Cardiovascular reactivity to the cold pressor test as a predictor of hypertension. In: Hypertension. 1989 ; Vol. 14, No. 5. pp. 524-530.
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