Cardiorespiratory fitness and incident diabetes

the FIT (Henry Ford ExercIse Testing) project

Stephen P. Juraschek, Michael Blaha, Roger S Blumenthal, Clinton Brawner, Waqas Qureshi, Steven J. Keteyian, John Schairer, Jonathan K. Ehrman, Mouaz H. Al-Mallah

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: Prior evidence has linked higher cardiorespiratory fitness with a lower risk of diabetes in ambulatory populations. Using a demographically diverse study sample, we examined the association of fitness with incident diabetes in 46,979 patients from The Henry Ford ExercIse Testing (FIT) Project without diabetes at baseline.

RESEARCH DESIGN AND METHODS: Fitness was measured during a clinician-referred treadmill stress test performed between 1991 and 2009. Incident diabetes was defined as a new diagnosis of diabetes on three separate consecutive encounters derived from electronic medical records or administrative claims files. Analyses were performed with Cox proportional hazards models and were adjusted for diabetes risk factors.

RESULTS: The mean age was 53 years with 48% women and 27% black patients. Mean metabolic equivalents (METs) achieved was 9.5 (SD 3.0). During a median follow-up period of 5.2 years (interquartile range 2.6-8.3 years), there were 6,851 new diabetes cases (14.6%). After adjustment, patients achieving ≥12 METs had a 54% lower risk of incident diabetes compared with patients achieving

CONCLUSIONS: These data demonstrate that higher fitness is associated with a lower risk of incident diabetes regardless of demographic characteristics and baseline risk factors. Future studies should examine the association between change in fitness over time and incident diabetes.

Original languageEnglish (US)
Pages (from-to)1075-1081
Number of pages7
JournalDiabetes Care
Volume38
Issue number6
DOIs
StatePublished - Jun 1 2015

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Metabolic Equivalent
Exercise
Exercise Test
Electronic Health Records
Proportional Hazards Models
Demography
Cardiorespiratory Fitness
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cardiorespiratory fitness and incident diabetes : the FIT (Henry Ford ExercIse Testing) project. / Juraschek, Stephen P.; Blaha, Michael; Blumenthal, Roger S; Brawner, Clinton; Qureshi, Waqas; Keteyian, Steven J.; Schairer, John; Ehrman, Jonathan K.; Al-Mallah, Mouaz H.

In: Diabetes Care, Vol. 38, No. 6, 01.06.2015, p. 1075-1081.

Research output: Contribution to journalArticle

Juraschek, SP, Blaha, M, Blumenthal, RS, Brawner, C, Qureshi, W, Keteyian, SJ, Schairer, J, Ehrman, JK & Al-Mallah, MH 2015, 'Cardiorespiratory fitness and incident diabetes: the FIT (Henry Ford ExercIse Testing) project', Diabetes Care, vol. 38, no. 6, pp. 1075-1081. https://doi.org/10.2337/dc14-2714
Juraschek, Stephen P. ; Blaha, Michael ; Blumenthal, Roger S ; Brawner, Clinton ; Qureshi, Waqas ; Keteyian, Steven J. ; Schairer, John ; Ehrman, Jonathan K. ; Al-Mallah, Mouaz H. / Cardiorespiratory fitness and incident diabetes : the FIT (Henry Ford ExercIse Testing) project. In: Diabetes Care. 2015 ; Vol. 38, No. 6. pp. 1075-1081.
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