Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis

Daniel Freitag, Adam S. Butterworth, Peter Willeit, Joanna M.M. Howson, Stephen Burgess, Stephen Kaptoge, Robin Young, Weang Kee Ho, Angela M. Wood, Michael Sweeting, Sarah Spackman, James R. Staley, Anna Ramond, Eric Harshfield, Sune F. Nielsen, Peer Grande, Leslie A. Lange, Matthew J. Bown, Gregory T. Jones, Robert A. ScottSteve Bevan, Eleonora Porcu, Gudmar Thorleifsson, Lingyao Zeng, Thorsten Kessler, Majid Nikpay, Ron Do, Weihua Zhang, Jemma C. Hopewell, Marcus Kleber, Graciela E. Delgado, Christopher P. Nelson, Anuj Goel, Joshua C. Bis, Abbas Dehghan, Symen Ligthart, Albert V. Smith, Liming Qu, Femke N.G. van 't Hof, Paul I.W. de Bakker, Annette F. Baas, Andre van Rij, Gerard Tromp, Helena Kuivaniemi, Marylyn D. Ritchie, Shefali S. Verma, Dana C. Crawford, Jennifer Malinowski, Mariza de Andrade, Iftikhar J. Kullo, Peggy L. Peissig, Catherine A. McCarty, Erwin P. Böttinger, Omri Gottesman, David R. Crosslin, David S. Carrell, Laura J. Rasmussen-Torvik, Jennifer A. Pacheco, Jie Huang, Nicholas J. Timpson, Johannes Kettunen, Mika Ala-Korpela, Gary F. Mitchell, Afshin Parsa, Ian B. Wilkinson, Mathias Gorski, Yong Li, Nora Franceschini, Margaux F. Keller, Santhi K. Ganesh, Carl D. Langefeld, Lucie Bruijn, Matthew A. Brown, David M. Evans, Svetlana Baltic, Manuel A. Ferreira, Hansjörg Baurecht, Stephan Weidinger, Andre Franke, Steven A. Lubitz, Martina Müller-Nurasyid, Janine F. Felix, Nicholas L. Smith, Marc Sudman, Susan D. Thompson, Eleftheria Zeggini, Kalliope Panoutsopoulou, Mike A. Nalls, Andrew Singleton, Constantin Polychronakos, Jonathan P. Bradfield, Hakon Hakonarson, Douglas F. Easton, Deborah Thompson, Ian P. Tomlinson, Malcolm Dunlop, Kari Hemminki, Gareth Morgan, Timothy Eisen, Hartmut Goldschmidt, James M. Allan, Marc Henrion, Nicola Whiffin, Yufei Wang, Daniel Chubb, Mark M. Iles, D. Timothy Bishop, Matthew H. Law, Nicholas K. Hayward, Yang Luo, Sergey Nejentsev, Maja Barbalic, David Crossman, Serena Sanna, Nicole Soranzo, Hugh S. Markus, Nicholas J. Wareham, Daniel J. Rader, Muredach Reilly, Themistocles Assimes, Tamara B. Harris, Albert Hofman, Oscar H. Franco, Vilmundur Gudnason, Russell Tracy, Bruce M. Psaty, Martin Farrall, Hugh Watkins, Alistair S. Hall, Nilesh J. Samani, Winfried März, Robert Clarke, Rory Collins, Jaspal S. Kooner, John C. Chambers, Sekar Kathiresan, Ruth McPherson, Jeanette Erdmann, Adnan Kastrati, Heribert Schunkert, Kári Stefánsson, Unnur Thorsteinsdottir, Jeremy D. Walston, Anne Tybjærg-Hansen, Dewan S. Alam, Abdullah Al Shafi Majumder, Emanuele Di Angelantonio, Rajiv Chowdhury, Børge G. Nordestgaard, Danish Saleheen, Simon G. Thompson, John Danesh, Richard S. Houlston

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