Cardiac responsiveness to chronotropic agents in the cobra, Naja naja L. Effect of temperature and thyroid hormones

James S.K. Sham, K. W. Chiu, Peter K.T. Pang

Research output: Contribution to journalArticle

Abstract

Cardiac responsiveness to isoproterenol, phenylephrine and parathyroid hormone have been studied in isolated cobra snake atria. The positive chronotropic responses to these agents are increased under elevated metabolic conditions: high temperature and tri-iodothyronine treatment. The enhanced cardiac reactivity provides greater cardiac output in animals with increased metabolic demands. In view of the different receptors being stimulated by these agents, theenhanced cardiac responsiveness is a general one and, most likely, a result of increased metabolism.

Original languageEnglish (US)
Pages (from-to)121-131
Number of pages11
JournalIntegrative and Comparative Biology
Volume27
Issue number1
DOIs
StatePublished - Dec 1 1987
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Plant Science

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