Cardiac responsiveness to chronotropic agents in the cobra, Naja naja L.

Effect of temperature and thyroid hormones

James Sham, K. W. Chiu, Peter K T Pang

Research output: Contribution to journalArticle

Abstract

Cardiac responsiveness to isoproterenol, phenylephrine and parathyroid hormone have been studied in isolated cobra snake atria. The positive chronotropic responses to these agents are increased under elevated metabolic conditions: high temperature and tri-iodothyronine treatment. The enhanced cardiac reactivity provides greater cardiac output in animals with increased metabolic demands. In view of the different receptors being stimulated by these agents, theenhanced cardiac responsiveness is a general one and, most likely, a result of increased metabolism.

Original languageEnglish (US)
Pages (from-to)121-131
Number of pages11
JournalIntegrative and Comparative Biology
Volume27
Issue number1
DOIs
StatePublished - 1987
Externally publishedYes

Fingerprint

Naja naja
Elapidae
phenylephrine
parathyroid hormone
hormones
Snakes
triiodothyronine
Phenylephrine
cardiac output
thyroid hormones
Hormones
Parathyroid Hormone
Thyroid Hormones
Isoproterenol
Cardiac Output
Cardiac
snakes
animal
receptors
Temperature

ASJC Scopus subject areas

  • Molecular Biology
  • Statistics and Probability
  • Computational Mathematics
  • Condensed Matter Physics
  • Social Sciences(all)
  • Plant Science
  • Animal Science and Zoology

Cite this

Cardiac responsiveness to chronotropic agents in the cobra, Naja naja L. Effect of temperature and thyroid hormones. / Sham, James; Chiu, K. W.; Pang, Peter K T.

In: Integrative and Comparative Biology, Vol. 27, No. 1, 1987, p. 121-131.

Research output: Contribution to journalArticle

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