Cardiac regeneration and stem cell therapy

Joshua M. Hare, Sandra V. Chaparro

Research output: Contribution to journalArticle

Abstract

PURPOSE OF REVIEW: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair. RECENT FINDINGS: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques. SUMMARY: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.

Original languageEnglish (US)
Pages (from-to)536-542
Number of pages7
JournalCurrent Opinion in Organ Transplantation
Volume13
Issue number5
DOIs
StatePublished - Oct 2008
Externally publishedYes

Fingerprint

Cardiac Myoblasts
Skeletal Myoblasts
Cell- and Tissue-Based Therapy
Bone Marrow Cells
Regeneration
Clinical Trials
Regenerative Medicine
Stem Cells

Keywords

  • Cardiac regeneration
  • Cell-based therapies
  • Stem cells

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation

Cite this

Cardiac regeneration and stem cell therapy. / Hare, Joshua M.; Chaparro, Sandra V.

In: Current Opinion in Organ Transplantation, Vol. 13, No. 5, 10.2008, p. 536-542.

Research output: Contribution to journalArticle

Hare, Joshua M. ; Chaparro, Sandra V. / Cardiac regeneration and stem cell therapy. In: Current Opinion in Organ Transplantation. 2008 ; Vol. 13, No. 5. pp. 536-542.
@article{246abdad49154347a896b36b871a9fbe,
title = "Cardiac regeneration and stem cell therapy",
abstract = "PURPOSE OF REVIEW: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair. RECENT FINDINGS: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques. SUMMARY: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.",
keywords = "Cardiac regeneration, Cell-based therapies, Stem cells",
author = "Hare, {Joshua M.} and Chaparro, {Sandra V.}",
year = "2008",
month = "10",
doi = "10.1097/MOT.0b013e32830fdfc4",
language = "English (US)",
volume = "13",
pages = "536--542",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Cardiac regeneration and stem cell therapy

AU - Hare, Joshua M.

AU - Chaparro, Sandra V.

PY - 2008/10

Y1 - 2008/10

N2 - PURPOSE OF REVIEW: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair. RECENT FINDINGS: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques. SUMMARY: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.

AB - PURPOSE OF REVIEW: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair. RECENT FINDINGS: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques. SUMMARY: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.

KW - Cardiac regeneration

KW - Cell-based therapies

KW - Stem cells

UR - http://www.scopus.com/inward/record.url?scp=60849104466&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=60849104466&partnerID=8YFLogxK

U2 - 10.1097/MOT.0b013e32830fdfc4

DO - 10.1097/MOT.0b013e32830fdfc4

M3 - Article

VL - 13

SP - 536

EP - 542

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 5

ER -