Cardiac regeneration and stem cell therapy

Joshua M. Hare, Sandra V. Chaparro

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


PURPOSE OF REVIEW: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair. RECENT FINDINGS: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques. SUMMARY: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.

Original languageEnglish (US)
Pages (from-to)536-542
Number of pages7
JournalCurrent Opinion in Organ Transplantation
Issue number5
StatePublished - Oct 2008
Externally publishedYes


  • Cardiac regeneration
  • Cell-based therapies
  • Stem cells

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation


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