Cardiac motion tracking using CINE harmonic phase (HARP) magnetic resonance imaging

Nael F. Osman, William S. Kerwin, Elliot R. McVeigh, Jerry L. Prince

Research output: Contribution to journalArticlepeer-review

511 Scopus citations


This article introduces a new image processing technique for rapid analysis of tagged cardiac magnetic resonance image sequences. The method uses isolated spectral peaks in SPAMM-tagged magnetic resonance images, which contain information about cardiac motion. The inverse Fourier transform of a spectral peak is a complex image whose calculated angle is called a harmonic phase (HARP) image. It is shown how two HARP image sequences can be used to automatically and accurately track material points through time. A rapid, semiautomated procedure to calculate circumferential and radial Lagrangian strain from tracked points is described. This new computational approach permits rapid analysis and visualization of myocardial strain within 5-10 min after the scan is complete. Its performance is demonstrated on MR image sequences reflecting both normal and abnormal cardiac motion. Results from the new method are shown to compare very well with a previously validated tracking algorithm.

Original languageEnglish (US)
Pages (from-to)1048-1060
Number of pages13
JournalMagnetic resonance in medicine
Issue number6
StatePublished - 1999


  • Cardiac motion
  • Harmonic phase
  • Magnetic resonance tagging
  • Myocardial strain

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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