Cardiac motion analysis in ischemic and non-ischemic cardiomyopathy using parallel transport

Siamak Ardekani, Robert G. Weiss, Albert C. Lardo, Richard T. George, Joao A.C. Lima, Katherine C. Wu, Michael I. Miller, Raimond L. Winslow, Laurent Younes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, we used multi-detector computed tomographic (MDCT) images of human left ventricles at end-diastole and end-systole to perform quantitative analysis and comparison of heart motion in patients with anterior wall myocardial infarction and ischemic cardiomyopathy (ICM) versus those with global non-ischemic cardiomyopathy (NICM). MDCT ventricular images of 25 patients (13 with ICM) with ejection fraction (EF) < 35% were analyzed. We used a novel technique (parallel transport) to translate within subject motion-related end-diastole to end-systole deformation to a common coordinate system without incorporating acrosssubject variation. We then performed a hypothesis testing on the ventricular motion variation in the global template coordinate. Statistical analysis indicated that there were meaningful ventricular motion differences between ICM and NICM groups. Additionally, patients with ICM demonstrated less wall thickening at ES in the anterior wall where the pathology was located.

Original languageEnglish (US)
Title of host publicationProceedings - 2009 IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2009
Pages899-902
Number of pages4
DOIs
StatePublished - Nov 17 2009
Event2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 - Boston, MA, United States
Duration: Jun 28 2009Jul 1 2009

Publication series

NameProceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009

Other

Other2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
CountryUnited States
CityBoston, MA
Period6/28/097/1/09

Keywords

  • Cardiac motion analysis
  • Cardiomyopathy
  • Parallel transport

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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    Ardekani, S., Weiss, R. G., Lardo, A. C., George, R. T., Lima, J. A. C., Wu, K. C., Miller, M. I., Winslow, R. L., & Younes, L. (2009). Cardiac motion analysis in ischemic and non-ischemic cardiomyopathy using parallel transport. In Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 (pp. 899-902). [5193198] (Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009). https://doi.org/10.1109/ISBI.2009.5193198