IRM de diffusion cardiaque dans l'Infarctus du myocarde récent et chronique: Expérience préliminaire

J. P. Laissy; J. M. Serfaty; D. Messika-Zeitoun; A. Ribet; S. Chillon; P. G. Steg; I. Klein

doi:10.1016/S0221-0363(09)74007-7

IRM de diffusion cardiaque dans l'Infarctus du myocarde récent et chronique: Expérience préliminaire

Translated title of the contribution: Cardiac diffusion MRI of acute and chronic myocardial infarction: Preliminary results

J. P. Laissy, J. M. Serfaty, D. Messika-Zeitoun, A. Ribet, S. Chillon, P. G. Steg, I. Klein

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Purpose: To use diffusion weighted MR imaging (DWI), a technique routinely used in patients with stroke, for diagnosis of myocardial infarction (MI). Materials and methods: A breath hold ECG gated DWI sequence (b=300 sec/mm ²) was developped and applied to 7 patients with recent MI (3-15 days), 3 patients with chronic MI (> 6 months) and 4 patients with valvular heart disease without MI (control cases). DWI data were correlated to T2W, first pass perfusion and delayed enhancement data. Results: In all patients with recent MI, DWI showed an area of increased signal with reduction of ADC relative to normal myocardium. Hyperintense lesion on DWI corresponded to areas of delayed enhancement. The diffusion images were normal in patients with chronic MI or no MI. Conclusion: Even though no animal model or other reference method is available, these preliminary results indicate that DWI could assist clinicians in detecting recent MI.

Translated title of the contribution	Cardiac diffusion MRI of acute and chronic myocardial infarction: Preliminary results
Original language	French
Pages (from-to)	481-484
Number of pages	4
Journal	Journal de Radiologie
Volume	90
Issue number	4
DOIs	https://doi.org/10.1016/S0221-0363(09)74007-7
State	Published - Apr 2009
Externally published	Yes

Keywords

Diffusion weighted MR imaging
Heart
Infarction, Myocardium
MRI
Viability

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

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10.1016/S0221-0363(09)74007-7

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title = "IRM de diffusion cardiaque dans l'Infarctus du myocarde r{\'e}cent et chronique: Exp{\'e}rience pr{\'e}liminaire",

abstract = "Purpose: To use diffusion weighted MR imaging (DWI), a technique routinely used in patients with stroke, for diagnosis of myocardial infarction (MI). Materials and methods: A breath hold ECG gated DWI sequence (b=300 sec/mm 2) was developped and applied to 7 patients with recent MI (3-15 days), 3 patients with chronic MI (> 6 months) and 4 patients with valvular heart disease without MI (control cases). DWI data were correlated to T2W, first pass perfusion and delayed enhancement data. Results: In all patients with recent MI, DWI showed an area of increased signal with reduction of ADC relative to normal myocardium. Hyperintense lesion on DWI corresponded to areas of delayed enhancement. The diffusion images were normal in patients with chronic MI or no MI. Conclusion: Even though no animal model or other reference method is available, these preliminary results indicate that DWI could assist clinicians in detecting recent MI.",

keywords = "Diffusion weighted MR imaging, Heart, Infarction, Myocardium, MRI, Viability",

author = "Laissy, {J. P.} and Serfaty, {J. M.} and D. Messika-Zeitoun and A. Ribet and S. Chillon and Steg, {P. G.} and I. Klein",

year = "2009",

month = apr,

doi = "10.1016/S0221-0363(09)74007-7",

language = "French",

volume = "90",

pages = "481--484",

journal = "Journal de Radiologie",

issn = "0221-0363",

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TY - JOUR

T1 - IRM de diffusion cardiaque dans l'Infarctus du myocarde récent et chronique

T2 - Expérience préliminaire

AU - Laissy, J. P.

AU - Serfaty, J. M.

AU - Messika-Zeitoun, D.

AU - Ribet, A.

AU - Chillon, S.

AU - Steg, P. G.

AU - Klein, I.

PY - 2009/4

Y1 - 2009/4

N2 - Purpose: To use diffusion weighted MR imaging (DWI), a technique routinely used in patients with stroke, for diagnosis of myocardial infarction (MI). Materials and methods: A breath hold ECG gated DWI sequence (b=300 sec/mm 2) was developped and applied to 7 patients with recent MI (3-15 days), 3 patients with chronic MI (> 6 months) and 4 patients with valvular heart disease without MI (control cases). DWI data were correlated to T2W, first pass perfusion and delayed enhancement data. Results: In all patients with recent MI, DWI showed an area of increased signal with reduction of ADC relative to normal myocardium. Hyperintense lesion on DWI corresponded to areas of delayed enhancement. The diffusion images were normal in patients with chronic MI or no MI. Conclusion: Even though no animal model or other reference method is available, these preliminary results indicate that DWI could assist clinicians in detecting recent MI.

AB - Purpose: To use diffusion weighted MR imaging (DWI), a technique routinely used in patients with stroke, for diagnosis of myocardial infarction (MI). Materials and methods: A breath hold ECG gated DWI sequence (b=300 sec/mm 2) was developped and applied to 7 patients with recent MI (3-15 days), 3 patients with chronic MI (> 6 months) and 4 patients with valvular heart disease without MI (control cases). DWI data were correlated to T2W, first pass perfusion and delayed enhancement data. Results: In all patients with recent MI, DWI showed an area of increased signal with reduction of ADC relative to normal myocardium. Hyperintense lesion on DWI corresponded to areas of delayed enhancement. The diffusion images were normal in patients with chronic MI or no MI. Conclusion: Even though no animal model or other reference method is available, these preliminary results indicate that DWI could assist clinicians in detecting recent MI.

KW - Diffusion weighted MR imaging

KW - Heart

KW - Infarction, Myocardium

KW - MRI

KW - Viability

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SN - 0221-0363

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JO - Journal de Radiologie

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ER -

IRM de diffusion cardiaque dans l'Infarctus du myocarde récent et chronique: Expérience préliminaire

Abstract

Keywords

ASJC Scopus subject areas

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