Cardiac CT in the Emergency Department: Contrasting Evidence from Registries and Randomized Controlled Trials

Nam Ju Lee, Harold Litt

Research output: Contribution to journalReview article

Abstract

Purpose of Review: To compare outcomes between registries and randomized controlled trials of coronary computed tomographic angiography (CCTA)-based versus standard of care approaches to the initial evaluation of patients with acute chest pain. Recent Findings: Randomized trials have demonstrated CCTA to be a safe and efficient tool for triage of low- to intermediate-risk patients presenting to the emergency department with chest pain. Recent studies demonstrate heterogeneous result using different standard of care approaches for evaluation of hard endpoints in comparison with standard evaluation. Also, there has been continued concern for increase in subsequent testing after coronary CTA. Summary: Although CCTA improves detection of coronary artery disease, it is uncertain if it will bring improvement of long-term health outcomes at this point of time. Careful analysis of the previous results and further investigation will be required to validate evaluation of hard endpoints.

Original languageEnglish (US)
Article number24
JournalCurrent Cardiology Reports
Volume20
Issue number4
DOIs
StatePublished - Apr 1 2018

Fingerprint

Registries
Hospital Emergency Service
Randomized Controlled Trials
Angiography
Standard of Care
Chest Pain
Triage
Acute Pain
Coronary Artery Disease
Health

Keywords

  • Cardiac
  • CCTA
  • Coronary
  • CT
  • Emergency department
  • Standard of care

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Cardiac CT in the Emergency Department : Contrasting Evidence from Registries and Randomized Controlled Trials. / Lee, Nam Ju; Litt, Harold.

In: Current Cardiology Reports, Vol. 20, No. 4, 24, 01.04.2018.

Research output: Contribution to journalReview article

@article{d9710d12ae4240f4a0849b9f1fce4c8c,
title = "Cardiac CT in the Emergency Department: Contrasting Evidence from Registries and Randomized Controlled Trials",
abstract = "Purpose of Review: To compare outcomes between registries and randomized controlled trials of coronary computed tomographic angiography (CCTA)-based versus standard of care approaches to the initial evaluation of patients with acute chest pain. Recent Findings: Randomized trials have demonstrated CCTA to be a safe and efficient tool for triage of low- to intermediate-risk patients presenting to the emergency department with chest pain. Recent studies demonstrate heterogeneous result using different standard of care approaches for evaluation of hard endpoints in comparison with standard evaluation. Also, there has been continued concern for increase in subsequent testing after coronary CTA. Summary: Although CCTA improves detection of coronary artery disease, it is uncertain if it will bring improvement of long-term health outcomes at this point of time. Careful analysis of the previous results and further investigation will be required to validate evaluation of hard endpoints.",
keywords = "Cardiac, CCTA, Coronary, CT, Emergency department, Standard of care",
author = "Lee, {Nam Ju} and Harold Litt",
year = "2018",
month = "4",
day = "1",
doi = "10.1007/s11886-018-0965-z",
language = "English (US)",
volume = "20",
journal = "Current Cardiology Reports",
issn = "1523-3782",
publisher = "Current Medicine Group",
number = "4",

}

TY - JOUR

T1 - Cardiac CT in the Emergency Department

T2 - Contrasting Evidence from Registries and Randomized Controlled Trials

AU - Lee, Nam Ju

AU - Litt, Harold

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Purpose of Review: To compare outcomes between registries and randomized controlled trials of coronary computed tomographic angiography (CCTA)-based versus standard of care approaches to the initial evaluation of patients with acute chest pain. Recent Findings: Randomized trials have demonstrated CCTA to be a safe and efficient tool for triage of low- to intermediate-risk patients presenting to the emergency department with chest pain. Recent studies demonstrate heterogeneous result using different standard of care approaches for evaluation of hard endpoints in comparison with standard evaluation. Also, there has been continued concern for increase in subsequent testing after coronary CTA. Summary: Although CCTA improves detection of coronary artery disease, it is uncertain if it will bring improvement of long-term health outcomes at this point of time. Careful analysis of the previous results and further investigation will be required to validate evaluation of hard endpoints.

AB - Purpose of Review: To compare outcomes between registries and randomized controlled trials of coronary computed tomographic angiography (CCTA)-based versus standard of care approaches to the initial evaluation of patients with acute chest pain. Recent Findings: Randomized trials have demonstrated CCTA to be a safe and efficient tool for triage of low- to intermediate-risk patients presenting to the emergency department with chest pain. Recent studies demonstrate heterogeneous result using different standard of care approaches for evaluation of hard endpoints in comparison with standard evaluation. Also, there has been continued concern for increase in subsequent testing after coronary CTA. Summary: Although CCTA improves detection of coronary artery disease, it is uncertain if it will bring improvement of long-term health outcomes at this point of time. Careful analysis of the previous results and further investigation will be required to validate evaluation of hard endpoints.

KW - Cardiac

KW - CCTA

KW - Coronary

KW - CT

KW - Emergency department

KW - Standard of care

UR - http://www.scopus.com/inward/record.url?scp=85043329091&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043329091&partnerID=8YFLogxK

U2 - 10.1007/s11886-018-0965-z

DO - 10.1007/s11886-018-0965-z

M3 - Review article

C2 - 29520449

AN - SCOPUS:85043329091

VL - 20

JO - Current Cardiology Reports

JF - Current Cardiology Reports

SN - 1523-3782

IS - 4

M1 - 24

ER -