Carcinoid heart disease without the carcinoid syndrome but with quadrivalvular regurgitation and unsuccessful operative intervention

William Clifford Roberts, Cyril Abie Varughese, Jong Mi Ko, Paul A. Grayburn, Robert Frederick Hebeler, Elizabeth C. Burton

Research output: Contribution to journalArticlepeer-review

Abstract

A 53-year-old woman is described who underwent mitral and aortic valve replacement and tricuspid valve annuloplasty for pure regurgitation at all 3 valve sites for unrecognized carcinoid heart disease without the carcinoid syndrome 22 days before death. Metastatic carcinoid was not recognized until necropsy, which disclosed a probable ovarian primary but with large hepatic metastases and left-sided cardiac involvement either greater than or equal to the right-sided involvement. Pulmonary hypertension, very unusual in carcinoid heart disease, persisted postoperatively and probably played a role in the patient's early death. Hepatic metastasis with ovarian primary is most unusual in this circumstance.

Original languageEnglish (US)
Pages (from-to)788-792
Number of pages5
JournalAmerican Journal of Cardiology
Volume107
Issue number5
DOIs
StatePublished - Mar 1 2011

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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