Capsular polysaccharides of Cryptococcus neoformans.

A. K. Bhattacharjee, J. E. Bennett, C. P. Glaudemans

Research output: Contribution to journalReview articlepeer-review


Polysaccharides of Cryptococcus neoformans are considered to have a role in the virulence of this encapsulated fungus. The structure has been determined for the most abundant polysaccharide, a glucuronoxylomannan of varying xylose and ester content. The structural complexity of the capsular material increases from serotype D to A to B to C, but even for the simplest capsule (type D), the immunodeterminants seem to occur only on the side chains. The interactions of some of these groups with antibodies is discussed.

Original languageEnglish (US)
Pages (from-to)619-624
Number of pages6
JournalReviews of infectious diseases
Issue number5
StatePublished - 1984

ASJC Scopus subject areas

  • Microbiology (medical)


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