TY - JOUR
T1 - Capsular polysaccharides of Cryptococcus neoformans.
AU - Bhattacharjee, A. K.
AU - Bennett, J. E.
AU - Glaudemans, C. P.
PY - 1984
Y1 - 1984
N2 - Polysaccharides of Cryptococcus neoformans are considered to have a role in the virulence of this encapsulated fungus. The structure has been determined for the most abundant polysaccharide, a glucuronoxylomannan of varying xylose and ester content. The structural complexity of the capsular material increases from serotype D to A to B to C, but even for the simplest capsule (type D), the immunodeterminants seem to occur only on the side chains. The interactions of some of these groups with antibodies is discussed.
AB - Polysaccharides of Cryptococcus neoformans are considered to have a role in the virulence of this encapsulated fungus. The structure has been determined for the most abundant polysaccharide, a glucuronoxylomannan of varying xylose and ester content. The structural complexity of the capsular material increases from serotype D to A to B to C, but even for the simplest capsule (type D), the immunodeterminants seem to occur only on the side chains. The interactions of some of these groups with antibodies is discussed.
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U2 - 10.1093/clinids/6.5.619
DO - 10.1093/clinids/6.5.619
M3 - Review article
C2 - 6209768
AN - SCOPUS:0021484764
SN - 0162-0886
VL - 6
SP - 619
EP - 624
JO - Reviews of infectious diseases
JF - Reviews of infectious diseases
IS - 5
ER -