Candidate selection, overall results, and choosing the right operation

Research output: Contribution to journalReview article

Abstract

Lung transplantation offers potential improvement in survival and improved quality of life in patients with end-stage lung disease. International guidelines for candidate selection have been agreed upon to aid physicians and providers in selecting appropriate candidates for lung transplantation. In recent years the U.S. lung allocation score (LAS) has been developed and implemented in an attempt to both maximize utility of scarce donor organs and provide benefit to those in need of lung transplantation. This has helped in the process of offering transplantation to those with the greatest need and best chance of survival. Appropriate lung transplantation candidates should have life-threatening lung disease but remain otherwise healthy, because significant comorbidities may increase the risk of poor outcomes after transplantation limiting long-term survival. Improved outcomes are seen through early referrals to a specialized center and vigilant evaluation to select the most appropriate candidates for lung transplantation.

Original languageEnglish (US)
Pages (from-to)99-107
Number of pages9
JournalSeminars in Respiratory and Critical Care Medicine
Volume31
Issue number2
DOIs
StatePublished - Apr 13 2010

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Keywords

  • Evaluation
  • Lung allocation score
  • Lung transplantation
  • Outcomes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

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