Cancer's molecular sweet tooth and the warburg effect

Jung Whan Kim, Chi V. Dang

Research output: Contribution to journalArticle

Abstract

More than 80 years ago, the renowned biochemist Otto Warburg described how cancer cells avidly consume glucose and produce lactic acid under aerobic conditions. Recent studies arguing that cancer cells benefit from this phenomenon, termed the Warburg effect, have renewed discussions about its exact role as cause, correlate, or facilitator of cancer. Molecular advances in this area may reveal tactics to exploit the cancer cell's "sweet tooth" for cancer therapy.

Original languageEnglish (US)
Pages (from-to)8927-8930
Number of pages4
JournalCancer Research
Volume66
Issue number18
DOIs
StatePublished - Sep 15 2006

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ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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