Cancer vaccines based on the identification of genes encoding cancer regression antigens

Steven A. Rosenberg

Research output: Contribution to journalReview articlepeer-review

372 Scopus citations

Abstract

The adoptive transfer of tumor-infiltrating lymphocytes (TILs) can mediate the regression of metastatic melanoma in humans. The genes encoding the antigens recognized by these TILs have been cloned and characterized. Here, Steven Rosenberg reviews how these genes and gene products are being used to develop new immunotherapies for the treatment of patients with cancer.

Original languageEnglish (US)
Pages (from-to)175-182
Number of pages8
JournalImmunology Today
Volume18
Issue number4
DOIs
StatePublished - Apr 1997
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

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