TY - JOUR
T1 - Cancer sequencing gets a little more personal
AU - Prokunina-Olsson, Ludmila
AU - Chanock, Stephen J.
PY - 2010/6/7
Y1 - 2010/6/7
N2 - In this Perspective, we discuss a paper in this issue of Science Translational Medicine, in which Leary and colleagues present a new method based on massive, parallel, and near-complete sequencing of individual tumor genomes. Their findings support the notion that cancer genomes house a spectrum of genetic alterations, many of which are unique to the individual tumor. More validation and a reduction in cost are required for this approach to become common in clinics.
AB - In this Perspective, we discuss a paper in this issue of Science Translational Medicine, in which Leary and colleagues present a new method based on massive, parallel, and near-complete sequencing of individual tumor genomes. Their findings support the notion that cancer genomes house a spectrum of genetic alterations, many of which are unique to the individual tumor. More validation and a reduction in cost are required for this approach to become common in clinics.
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UR - http://www.scopus.com/inward/citedby.url?scp=77952971405&partnerID=8YFLogxK
U2 - 10.1126/scitranslmed.3000929
DO - 10.1126/scitranslmed.3000929
M3 - Short survey
C2 - 20371489
AN - SCOPUS:77952971405
SN - 1946-6234
VL - 2
SP - 20ps8
JO - Science Translational Medicine
JF - Science Translational Medicine
IS - 20
ER -