Cancer Imaging at the Crossroads of Precision Medicine: Perspective from an Academic Imaging Department in a Comprehensive Cancer Center

Annick D. Van Den Abbeele, Katherine M. Krajewski, Sree Harsha Tirumani, Fiona M. Fennessy, Pamela J. DiPiro, Quang Dé Nguyen, Gordon J. Harris, Heather A. Jacene, Greg Lefever, Nikhil H. Ramaiya

Research output: Contribution to journalArticlepeer-review

Abstract

The authors propose one possible vision for the transformative role that cancer imaging in an academic setting can play in the current era of personalized and precision medicine by sharing a conceptual model that is based on experience and lessons learned designing a multidisciplinary, integrated clinical and research practice at their institution. The authors' practice and focus are disease-centric rather than imaging-centric. A "wall-less" infrastructure has been developed, with bidirectional integration of preclinical and clinical cancer imaging research platforms, enabling rapid translation of novel cancer drugs from discovery to clinical trial evaluation. The talents and expertise of medical professionals, scientists, and staff members have been coordinated in a horizontal and vertical fashion through the creation of Cancer Imaging Consultation Services and the "Adopt-a-Radiologist" campaign. Subspecialized imaging consultation services at the hub of an outpatient cancer center facilitate patient decision support and management at the point of care. The Adopt-a-Radiologist campaign has led to the creation of a novel generation of imaging clinician-scientists, fostered new collaborations, increased clinical and academic productivity, and improved employee satisfaction. Translational cancer research is supported, with a focus on early in vivo testing of novel cancer drugs, co-clinical trials, and longitudinal tumor imaging metrics through the imaging research core laboratory. Finally, a dedicated cancer imaging fellowship has been developed, promoting the future generation of cancer imaging specialists as multidisciplinary, multitalented professionals who are trained to effectively communicate with clinical colleagues and positively influence patient care.

Original languageEnglish (US)
Pages (from-to)365-371
Number of pages7
JournalJournal of the American College of Radiology
Volume13
Issue number4
DOIs
StatePublished - Apr 1 2016

Keywords

  • Cancer imaging
  • disease-centric
  • multidisciplinary
  • precision medicine
  • training

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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