Cancer Genomics: From Bench to Personalized Medicine

Graham Dellaire, Jason N. Berman, Robert Arceci

Research output: Book/ReportBook

Abstract

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment.

Original languageEnglish (US)
PublisherElsevier Inc.
Number of pages494
ISBN (Print)9780123969675
StatePublished - Dec 2013
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Dellaire, G., Berman, J. N., & Arceci, R. (2013). Cancer Genomics: From Bench to Personalized Medicine. Elsevier Inc.