Cancer genes and the pathways they control

Research output: Contribution to journalArticle

Abstract

The revolution in cancer research can be summed up in a single sentence: cancer is, in essence, a genetic disease. In the last decade, many important genes responsible for the genesis of various cancers have been discovered, their mutations precisely identified, and the pathways through which they act characterized. The purposes of this review are to highlight examples of progress in these areas, indicate where knowledge is scarce and point out fertile grounds for future investigation.

Original languageEnglish (US)
Pages (from-to)789-799
Number of pages11
JournalNature Medicine
Volume10
Issue number8
DOIs
StatePublished - Aug 2004

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Neoplasm Genes
Genes
Neoplasms
Inborn Genetic Diseases
Mutation
Research

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Cancer genes and the pathways they control. / Vogelstein, Bert; Kinzler, Kenneth W.

In: Nature Medicine, Vol. 10, No. 8, 08.2004, p. 789-799.

Research output: Contribution to journalArticle

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