Can we rely on the antiretroviral treatment as the only means for human immunodeficiency virus prevention? A Public Health perspective

Antons Mozalevskis, Sandra Manzanares-Laya, Patricia García De Olalla, Antonio Moreno, Constanza Jacques-Aviñó, Joan A. Caylà

Research output: Contribution to journalArticle

Abstract

The evidence that supports the preventive effect of combination antiretroviral treatment (cART) in HIV sexual transmission suggested the so-called 'treatment as prevention' (TAP) strategy as a promising tool for slowing down HIV transmission. As the messages and attitudes towards condom use in the context of TAP appear to be somehow confusing, the aim here is to assess whether relying on cART alone to prevent HIV transmission can currently be recommended from the Public Health perspective. A review is made of the literature on the effects of TAP strategy on HIV transmission and the epidemiology of other sexual transmitted infections (STIs) in the cART era, and recommendations from Public Health institutions on the TAP as of February 2014. The evolution of HIV and other STIs in Barcelona from 2007 to 2012 has also been analysed. Given that the widespread use of cART has coincided with an increasing incidence of HIV and other STIs, mainly amongst men who have sex with men, a combination and diversified prevention methods should always be considered and recommended in counselling. An informed decision on whether to stop using condoms should only be made by partners within stable couples, and after receiving all the up-to-date information regarding TAP. From the public health perspective, primary prevention should be a priority; therefore relying on cART alone is not a sufficient strategy to prevent new HIV and other STIs.

Original languageEnglish (US)
Pages (from-to)e63-e68
JournalEnfermedades Infecciosas y Microbiologia Clinica
Volume33
Issue number9
DOIs
StatePublished - 2015
Externally publishedYes

Fingerprint

Public Health
HIV
Therapeutics
Condoms
Infection
Primary Prevention
Counseling
Epidemiology
Incidence

Keywords

  • Antiretroviral treatment
  • Human immunodeficiency virus
  • Prevention
  • Sexually transmitted infections

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Can we rely on the antiretroviral treatment as the only means for human immunodeficiency virus prevention? A Public Health perspective. / Mozalevskis, Antons; Manzanares-Laya, Sandra; García De Olalla, Patricia; Moreno, Antonio; Jacques-Aviñó, Constanza; Caylà, Joan A.

In: Enfermedades Infecciosas y Microbiologia Clinica, Vol. 33, No. 9, 2015, p. e63-e68.

Research output: Contribution to journalArticle

Mozalevskis, Antons ; Manzanares-Laya, Sandra ; García De Olalla, Patricia ; Moreno, Antonio ; Jacques-Aviñó, Constanza ; Caylà, Joan A. / Can we rely on the antiretroviral treatment as the only means for human immunodeficiency virus prevention? A Public Health perspective. In: Enfermedades Infecciosas y Microbiologia Clinica. 2015 ; Vol. 33, No. 9. pp. e63-e68.
@article{00493195cee342c5a1551f191b8cd2dd,
title = "Can we rely on the antiretroviral treatment as the only means for human immunodeficiency virus prevention? A Public Health perspective",
abstract = "The evidence that supports the preventive effect of combination antiretroviral treatment (cART) in HIV sexual transmission suggested the so-called 'treatment as prevention' (TAP) strategy as a promising tool for slowing down HIV transmission. As the messages and attitudes towards condom use in the context of TAP appear to be somehow confusing, the aim here is to assess whether relying on cART alone to prevent HIV transmission can currently be recommended from the Public Health perspective. A review is made of the literature on the effects of TAP strategy on HIV transmission and the epidemiology of other sexual transmitted infections (STIs) in the cART era, and recommendations from Public Health institutions on the TAP as of February 2014. The evolution of HIV and other STIs in Barcelona from 2007 to 2012 has also been analysed. Given that the widespread use of cART has coincided with an increasing incidence of HIV and other STIs, mainly amongst men who have sex with men, a combination and diversified prevention methods should always be considered and recommended in counselling. An informed decision on whether to stop using condoms should only be made by partners within stable couples, and after receiving all the up-to-date information regarding TAP. From the public health perspective, primary prevention should be a priority; therefore relying on cART alone is not a sufficient strategy to prevent new HIV and other STIs.",
keywords = "Antiretroviral treatment, Human immunodeficiency virus, Prevention, Sexually transmitted infections",
author = "Antons Mozalevskis and Sandra Manzanares-Laya and {Garc{\'i}a De Olalla}, Patricia and Antonio Moreno and Constanza Jacques-Avi{\~n}{\'o} and Cayl{\`a}, {Joan A.}",
year = "2015",
doi = "10.1016/j.eimc.2014.07.014",
language = "English (US)",
volume = "33",
pages = "e63--e68",
journal = "Enfermedades Infecciosas y Microbiologia Clinica",
issn = "0213-005X",
publisher = "Ediciones Doyma, S.L.",
number = "9",

}

TY - JOUR

T1 - Can we rely on the antiretroviral treatment as the only means for human immunodeficiency virus prevention? A Public Health perspective

AU - Mozalevskis, Antons

AU - Manzanares-Laya, Sandra

AU - García De Olalla, Patricia

AU - Moreno, Antonio

AU - Jacques-Aviñó, Constanza

AU - Caylà, Joan A.

PY - 2015

Y1 - 2015

N2 - The evidence that supports the preventive effect of combination antiretroviral treatment (cART) in HIV sexual transmission suggested the so-called 'treatment as prevention' (TAP) strategy as a promising tool for slowing down HIV transmission. As the messages and attitudes towards condom use in the context of TAP appear to be somehow confusing, the aim here is to assess whether relying on cART alone to prevent HIV transmission can currently be recommended from the Public Health perspective. A review is made of the literature on the effects of TAP strategy on HIV transmission and the epidemiology of other sexual transmitted infections (STIs) in the cART era, and recommendations from Public Health institutions on the TAP as of February 2014. The evolution of HIV and other STIs in Barcelona from 2007 to 2012 has also been analysed. Given that the widespread use of cART has coincided with an increasing incidence of HIV and other STIs, mainly amongst men who have sex with men, a combination and diversified prevention methods should always be considered and recommended in counselling. An informed decision on whether to stop using condoms should only be made by partners within stable couples, and after receiving all the up-to-date information regarding TAP. From the public health perspective, primary prevention should be a priority; therefore relying on cART alone is not a sufficient strategy to prevent new HIV and other STIs.

AB - The evidence that supports the preventive effect of combination antiretroviral treatment (cART) in HIV sexual transmission suggested the so-called 'treatment as prevention' (TAP) strategy as a promising tool for slowing down HIV transmission. As the messages and attitudes towards condom use in the context of TAP appear to be somehow confusing, the aim here is to assess whether relying on cART alone to prevent HIV transmission can currently be recommended from the Public Health perspective. A review is made of the literature on the effects of TAP strategy on HIV transmission and the epidemiology of other sexual transmitted infections (STIs) in the cART era, and recommendations from Public Health institutions on the TAP as of February 2014. The evolution of HIV and other STIs in Barcelona from 2007 to 2012 has also been analysed. Given that the widespread use of cART has coincided with an increasing incidence of HIV and other STIs, mainly amongst men who have sex with men, a combination and diversified prevention methods should always be considered and recommended in counselling. An informed decision on whether to stop using condoms should only be made by partners within stable couples, and after receiving all the up-to-date information regarding TAP. From the public health perspective, primary prevention should be a priority; therefore relying on cART alone is not a sufficient strategy to prevent new HIV and other STIs.

KW - Antiretroviral treatment

KW - Human immunodeficiency virus

KW - Prevention

KW - Sexually transmitted infections

UR - http://www.scopus.com/inward/record.url?scp=84952977951&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84952977951&partnerID=8YFLogxK

U2 - 10.1016/j.eimc.2014.07.014

DO - 10.1016/j.eimc.2014.07.014

M3 - Article

VL - 33

SP - e63-e68

JO - Enfermedades Infecciosas y Microbiologia Clinica

JF - Enfermedades Infecciosas y Microbiologia Clinica

SN - 0213-005X

IS - 9

ER -