Can matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF) enhance antimicrobial stewardship efforts in the acute care setting?

Pranita Tamma, Kennard Tan, Veronique R. Nussenblatt, Alison Turnbull, Karen C Carroll, Sara Cosgrove

Research output: Contribution to journalArticle

Abstract

We evaluated 222 hospitalized patients whose clinical isolates were tested using standard methods and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF). MALDI-TOF could have reduced time to appropriate therapy for 28.8% and 44.6% patients based on the treating physician's choices and stewardship team recommendations, respectively. Clinicians should be aware of scenarios in which MALDI-TOF can optimize antibiotic therapy.

Original languageEnglish (US)
Pages (from-to)990-995
Number of pages6
JournalInfection Control and Hospital Epidemiology
Volume34
Issue number9
DOIs
Publication statusPublished - Sep 2013

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Epidemiology
  • Infectious Diseases

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