TY - JOUR
T1 - Callosal and association neurons in the cortical space
T2 - A spectral analysis approach
AU - Caminiti, Roberto
AU - Johnson, Paul B.
AU - Urbano, Antonio
AU - Georgopoulos, Apostolos P.
AU - Zeger, Scott
N1 - Funding Information:
This study was supported in part by the Consiglio Nazionale delle Ricerche, Rome, Italy, and by United States PHS Grant NS17413.
PY - 1988/9/15
Y1 - 1988/9/15
N2 - The tangential distributions of callosal neurons of area 5 projecting homotopically to the contralateral hemisphere and of association neurons of areas 4 and 6 projecting to ipsilateral area 5 were determined in the macaque monkey by using neuroanatomical methods based on the retrograde transport of horseradish peroxidase. Both distributions were studied qualitatively through 2-dimensional reconstructions of the cortical areas of origin and quantitatively through a spectral analysis. This approach facilitated the characterization of the spatial periodicities contained in these distributions revealing that, in area 5, callosal neurons were organized in bands of various shapes and width; these bands were composed of more discrete clusters of cells. In the frontal lobe, association neurons projecting to ipsilateral area 5 were arranged similarly. This study suggests that a common principle underlies the tangential organization of both callosal and association projecting cells in different cortical areas and emphasizes a basic similarity of interhemispheric and intrahemispheric connections.
AB - The tangential distributions of callosal neurons of area 5 projecting homotopically to the contralateral hemisphere and of association neurons of areas 4 and 6 projecting to ipsilateral area 5 were determined in the macaque monkey by using neuroanatomical methods based on the retrograde transport of horseradish peroxidase. Both distributions were studied qualitatively through 2-dimensional reconstructions of the cortical areas of origin and quantitatively through a spectral analysis. This approach facilitated the characterization of the spatial periodicities contained in these distributions revealing that, in area 5, callosal neurons were organized in bands of various shapes and width; these bands were composed of more discrete clusters of cells. In the frontal lobe, association neurons projecting to ipsilateral area 5 were arranged similarly. This study suggests that a common principle underlies the tangential organization of both callosal and association projecting cells in different cortical areas and emphasizes a basic similarity of interhemispheric and intrahemispheric connections.
KW - Association efferent zone
KW - Callosal efferent zone
KW - Fourier analysis
KW - Tangential distribution of efferent cortical neurons
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U2 - 10.1016/0166-4328(88)90148-9
DO - 10.1016/0166-4328(88)90148-9
M3 - Article
C2 - 3166717
AN - SCOPUS:0023767421
SN - 0166-4328
VL - 30
SP - 193
EP - 201
JO - Behavioural Brain Research
JF - Behavioural Brain Research
IS - 2
ER -