Calculation of three-dimensional left ventricular strains from biplanar tagged MR images.

C. C. Moore, W. G. O'Dell, E. R. McVeigh, Elias Zerhouni

Research output: Contribution to journalArticle


The noninvasive measurement of time-resolved three-dimensional (3D) strains throughout the myocardium could greatly improve the clinical evaluation of cardiac disease and the ability to mathematically model the heart. On the basis of orthogonal arrays of tagged magnetic resonance (MR) images taken at several times during systole, such strains can be determined, but only after heart motion through the image planes is taken into account. An iterative material point-tracking algorithm is presented to solve this problem. It is tested by means of mathematical models of the heart with cylindric and spherical geometries that undergo deformations and bulk motions. Errors introduced by point-tracking interpolation were found to be negligible compared with those due to marker identification on the images. In a human heart studied with this technique, the corrected radial strains at the left ventricular base were approximately 2.5 times the two-dimensional estimates derived from the fixed image planes. The authors conclude that material point tracking allows accurate, time-resolved 3D strains to be calculated from tagged MR images, and that prior correction for motion of the heart through image planes is necessary.

Original languageEnglish (US)
Pages (from-to)165-175
Number of pages11
JournalJournal of Magnetic Resonance Imaging
Issue number2
StatePublished - Mar 1992


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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