Abstract
An algorithmic solution to the biological effective dose (BED) calculation from the Lea-Catcheside formula for a piecewise defined function is presented. Data from patients treated for metastatic thyroid cancer were used to illustrate the solution. The Lea-Catcheside formula for the G -factor of the BED is integrated numerically using a large number of small trapezoidal fits to each integral. The algorithmically calculated BED is compatible with an analytic calculation for a similarly valued exponentially fitted dose-rate plot and is the only resolution for piecewise defined dose-rate functions.
Original language | English (US) |
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Pages (from-to) | 904-907 |
Number of pages | 4 |
Journal | Medical physics |
Volume | 36 |
Issue number | 3 |
DOIs | |
State | Published - 2009 |
ASJC Scopus subject areas
- Biophysics
- Radiology Nuclear Medicine and imaging