Calcium transport in isolated sarcoplasmic reticulum during muscle maturation [23]

Barry L. Fanburg, Daniel B. Drachman, David Moll, Sanford I. Roth

Research output: Contribution to journalLetter

Abstract

THERE is abundant evidence that the sarcoplasmic reticulum (SR) of skeletal muscle plays an important part in excitation-contraction coupling and in relaxation of muscle fibres1. It is usually accepted that the ability of this membrane system to transport calcium ions rapidly in the immediate vicinity of the contractile proteins accounts for its effects. Thus release of calcium from SR to myofilaments leads to muscle contraction; removal and sequestration of calcium by the reticulum bring about relaxation.

Original languageEnglish (US)
Pages (from-to)962-964
Number of pages3
JournalNature
Volume218
Issue number5145
DOIs
StatePublished - Dec 1 1968
Externally publishedYes

ASJC Scopus subject areas

  • General

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