Calcium channel blockade in older diabetic hypertensives

J. A. Staessen, W. H. Birkenhager, J. Gasowski, P. W. De Leeuw, W. S. Post

Research output: Contribution to journalReview articlepeer-review


The authors wished to define the role of calcium channel blocking agents in preventing cardiovascular sequela in patients with diabetes mellitus and hypertension. They collected data from three sources: (1) post hoc analyses of diabetic subgroups in placebo-controlled hypertension trials (SHEP, Syst- Eur, Syst-China), (2) a stepped-care blood pressure trial (HOT), and (3) comparative trials primarily focused on metabolic aspects and intermediate end points (ABCD, FACET). The data indicate that long-acting calcium channel blockers perform well in preventing cardiovascular complications in diabetic hypertensive patients.

Original languageEnglish (US)
Pages (from-to)39-45
Number of pages7
JournalCardiology Review
Issue number11
StatePublished - Jan 1 1999
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Calcium channel blockade in older diabetic hypertensives'. Together they form a unique fingerprint.

Cite this