Calcium channel blockade in older diabetic hypertensives

J. A. Staessen, W. H. Birkenhager, J. Gasowski, P. W. De Leeuw, Wendy S Post

Research output: Contribution to journalReview article


The authors wished to define the role of calcium channel blocking agents in preventing cardiovascular sequela in patients with diabetes mellitus and hypertension. They collected data from three sources: (1) post hoc analyses of diabetic subgroups in placebo-controlled hypertension trials (SHEP, Syst- Eur, Syst-China), (2) a stepped-care blood pressure trial (HOT), and (3) comparative trials primarily focused on metabolic aspects and intermediate end points (ABCD, FACET). The data indicate that long-acting calcium channel blockers perform well in preventing cardiovascular complications in diabetic hypertensive patients.

Original languageEnglish (US)
Pages (from-to)39-45
Number of pages7
JournalCardiology Review
Issue number11
StatePublished - 1999
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Staessen, J. A., Birkenhager, W. H., Gasowski, J., De Leeuw, P. W., & Post, W. S. (1999). Calcium channel blockade in older diabetic hypertensives. Cardiology Review, 16(11), 39-45.