The authors wished to define the role of calcium channel blocking agents in preventing cardiovascular sequela in patients with diabetes mellitus and hypertension. They collected data from three sources: (1) post hoc analyses of diabetic subgroups in placebo-controlled hypertension trials (SHEP, Syst- Eur, Syst-China), (2) a stepped-care blood pressure trial (HOT), and (3) comparative trials primarily focused on metabolic aspects and intermediate end points (ABCD, FACET). The data indicate that long-acting calcium channel blockers perform well in preventing cardiovascular complications in diabetic hypertensive patients.
|Original language||English (US)|
|Number of pages||7|
|State||Published - 1999|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine