Cabergoline therapy for cushing disease throughout pregnancy

Irene Woo, Robert M. Ehsanipoor

Research output: Contribution to journalArticle

Abstract

Background: Cushing disease during pregnancy is rare and is associated with significant maternal and fetal morbidity and mortality. Transsphenoidal pituitary surgery is the first-line therapy; however, in cases of failed surgery or in patients who are not surgical candidates, medical therapy has been used to control symptoms. Case: A 29-year-old woman with Cushing disease and a noncurative transsphenoidal pituitary surgery was successfully treated with cabergoline, a dopamine agonist. After approximately 1 year of therapy, she became pregnant. She was maintained on high-dose cabergoline throughout her pregnancy and had an uncomplicated antenatal course. She went into spontaneous labor at 38 weeks of gestation and delivered a healthy female neonate. Conclusion: Cabergoline can be used to manage Cushing disease successfully during pregnancy with an opportunity for a favorable outcome.

Original languageEnglish (US)
Pages (from-to)485-487
Number of pages3
JournalObstetrics and gynecology
Volume122
Issue number2 PART2
DOIs
StatePublished - Aug 1 2013

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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