C9ORF72-ALS/FTD: Transgenic Mice Make a Come-BAC

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations


For five years, since the landmark discovery of the C9ORF72 hexanucleotide repeat expansion in ALS/FTD, a transgenic mouse model has remained elusive. Now, two laboratories (. Liu et al., 2016; Jiang et al., 2016) report the development of BAC transgenic mice that recapitulate features of the human disease.

Original languageEnglish (US)
Pages (from-to)427-431
Number of pages5
Issue number3
StatePublished - May 4 2016

ASJC Scopus subject areas

  • Neuroscience(all)


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