C substance - specific, latex agglutination for early and rapid detection of Streptococcus pneumoniae in blood cultures

M. V. Jesudason, G. Sridharan, K. Arulselvan, A. Joseph, M. C. Steinhoff, T. J. John

Research output: Contribution to journalArticlepeer-review

Abstract

A slide agglutination test was developed using latex particles coated with antiserum against the C substance, a common antigen for all serotypes of Streptococcus pneumoniae. This test was used for the rapid identification of pneumococci in blood culture broths which contained Gram positive cocci (GPC) in pairs or short chains on smear examination. Of 238 consecutive blood cultures with GPC tested, 72 were positive for Strep. pneumoniae by the latex test and conventional methods. The remaining 166 cultures were negative for both these, indicating a 100 per cent specificity and sensitivity for the test.

Original languageEnglish (US)
Pages (from-to)258-260
Number of pages3
JournalIndian Journal of Medical Research
Volume102
Issue numberDEC.
StatePublished - Dec 1 1995

Keywords

  • Blood culture
  • Latex agglutination
  • Streptococcus pneumoniae

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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